响应面法优化人工蛹虫草子实体中虫草酸微波提取工艺  

Optimization of Microwave Extraction of Cordycepic Acid in Cultured Cordyceps militaris by Response Surface Methodology

作　　者：邓黎[1] 韩涛[1] 王晓虹[1] 皮立[1] 韩发[1] 

机构地区：[1]中国科学院西北高原生物研究所,西宁810008

出　　处：《天然产物研究与开发》2013年第9期1249-1254,共6页Natural Product Research and Development

基　　金：中科院院地合作项目(Y12B031211);科技部人员服务企业行动项目(2009GJG20004);中科院科技支青项目(082B371211);国家自然科学基金项目(31070475)

摘　　要：为优化人工蛹虫草子实体中虫草酸的微波提取工艺,在单因素试验基础上,利用响应曲面法考察提取时间、微波功率和液固比对虫草酸提取率的影响,优化提取工艺。结果表明:人工培养蛹虫草子实体中虫草酸微波提取的优化工艺条件为:微波功率555 W,液固比35 mL/g,提取时间4 min,提取2次,虫草酸提取率的理论值可达84.45%。This paper was aiming to optimize the microwave extraction of cordyceps acid from cultured Cordyceps milita- r/s. On the basis of single-factor test, the effects of extraction duration, microwave power and the ratio of material to liquid on the extraction yield of cordyceps acid were investigated using response surface methodology. The results showed that the optimal conditions for the extraction of cordyceps acid were：microwave power of 555 W, the ratio material to liquid of 35 mL/g, extraction time of 4 rain, with twice extraction. Under the optimal extraction conditions, the theoretical extrac- tion rate of cordyceps acid was up to 84.45%.

关 键 词：蛹虫草 虫草酸 微波提取 响应曲面法 

分 类 号：TS201.1[轻工技术与工程—食品科学]