差示扫描量热法在药物定性分析中的应用  

Application of differential scanning calorimetry in pharmaceutical qualitative analysis

作　　者：王杰晶[1] 李银峰[2] 李佩[3] 张园园[3] 靳朝东[2] 

机构地区：[1]河南大学,河南开封475001 [2]天津药物研究院分析测试中心,天津300193 [3]天津中医药大学,天津300193

出　　处：《现代药物与临床》2013年第5期815-818,共4页Drugs & Clinic

摘　　要：差示扫描量热法(DSC)是在程序控制温度下,测量输给物质和参比物的功率差与温度关系的一种技术,被广泛应用于药品的研究生产和质量测试的快速可靠的热分析方法,该方法具有准确快速、样品用量少及易于操作等特点。综述了近年来差示扫描量热法在化学原料药、药物制剂、生物制品以及中药鉴定等方面的应用,并展望了未来的发展前景。Differential scanning calorimetry（DSC） is a technology to measure the loss to the power of substance and reference substance poor relations with the temperature under the program control temperature,and it is widely used in pharmaceutical research production and quality test.This method is fast,accurate,and easy to operate with fewer samples.This article gives a short overview on the application of DSC in chemical raw medicine,pharmaceutical preparation,biological product,and identification of Chinese materia medica,and looking forward to the prospect of the development in future.

关 键 词：差示扫描量热法 化学原料药 药物制剂 生物制品 中药鉴定 

分 类 号：R927.1[医药卫生—药学]