水提薛荔籽果胶对去势雌性大鼠肠道健康的影响  

Effect of water-based extraction of pectin from Ficus Pumila L.Seeds on bowel health in ovariectomized rats

作　　者：唐艳[1] 桂余[1] 任文瑾[1] 彭林[1] 刘雄[1] 

机构地区：[1]西南大学食品科学学院,重庆北碚400715

出　　处：《食品工业科技》2013年第21期347-351,356,共6页Science and Technology of Food Industry

基　　金：教育部留学归国人员启动项目(教外司留[2010]1174)

摘　　要：目的:研究水提薛荔籽果胶对去势雌性大鼠肠道健康的影响。方法:将32只雌性SD大鼠按体重随机分为4组:卵巢伪切除组(Sham组)、卵巢切除对照组(OVX-CN组)、15%薛荔籽果胶OVX组(FPLP组)、15%柑橘果胶OVX组(CP组),分别测定大鼠盲肠组织、游离氨、短链脂肪酸(SCFA)以及微生物数量等反映肠道健康的指标。结果:与OVX空白组比较,FPLP组和CP组能显著增加去势雌性大鼠粪便量、盲肠内容物重、壁湿重(p<0.01),降低游离氨量(p<0.05),增加肠道内厌氧菌、乳酸杆菌、双歧杆菌数量,升高有益菌与有害菌比例。SCFA含量都有增加的趋势,除了CP组丁酸与OVX空白组没有差别外,FPLP组和CP组盲肠中SCFA含量与盲肠中OVX空白组相比都显著增加(p<0.05)。结论:水提薛荔籽果胶能改善去势雌性大鼠肠道健康。Objective：To investgate the effect of water-based extraction of Ficus Pumila L.Seeds Pectin on bowel health in ovariectomized rats.Methods：Twenty-four healthy female SD rats were randomly assigned into sham- ovariectomized group,ovariectomized group as model control, 15% Ficus Pumila L.Seeds Pectin ovariectomized group,J5% Citrus Pectin ovariectomized group. Large bowel function was evaluated by determination of cecum tissues, pH value, short-chain fatty acids（ SCFA）, ect.Results. Compared with model control group, fecal bulk and cecum contents and cecum weight of Ficus Pumila L.Seeds Pectin group and Citrus Pectin group were higher dose- dependently, and decreased the free ammonia of cecum contents, and increased the amount of Anaerobes and Lactobacillus and Bifidobacterium, and increased the proportion of beneficial bacteria and inhibited harmful bacteria in intestinal environment.SCFA level of cecum was higher in Ficus Pumila L.Seeds Pectin group and Citrus Pectin group compared with model control group except butyric acid of cecum in Citrus Pectin group.Conclusion. water-based extraction of Pumila L.Seeds Pectin could improve the large bowel health in ovariectomized rats.

关 键 词：薛荔籽果胶 肠道发酵 短链脂肪酸 肠道菌群 

分 类 号：TS201.4[轻工技术与工程—食品科学]