基于β-环糊精和二茂铁的电压刺激响应体系  

Voltage-Responsive Systems Based on β-Cyclodextrin and Ferrocene

作　　者：彭了 冯岸超[1] 王宏[1] 张慧娟[2] 袁金颖[1] 

机构地区：[1]清华大学化学系有机光电子与分子工程教育部重点实验室,北京100084 [2]北京工商大学材料与机械工程学院,北京100048

出　　处：《化学进展》2013年第11期1942-1950,共9页Progress in Chemistry

基　　金：国家自然科学基金项目(No.21174076;21104040;51073090);国家重点基础研究发展计划(973)项目(No.2009CB930602)资助

摘　　要：刺激响应聚合物是当今材料科学研究的热点之一,其能够感受外界刺激,以自身的物理或者化学性质发生变化作为响应,在药物可控释放和生物传感器等方面有广阔的应用。电压刺激是一种清洁而简单的刺激方式,在生物医学领域中有潜在应用,具有重要的研究价值。基于β-环糊精和二茂铁的体系是目前研究最多的电压刺激响应体系。本文综述了该体系近期的相关工作,从该体系的响应原理、结构、表征和应用四个方面进行了论述,并就该体系的改进和发展进行了展望。Stimuli-responsive polymer is one of the hot research topics in material science. These polymers are able to respond to external stimulation, such as light, molecules, redox, pH, temperature and so on. They undergo physical or chemical changes, for example, gel-sol transition and change of volume, so they can be widely applied in controlled drug release and biosensors. Voltage stimulation can change the host-guest interaction through electron transfer reactions to add or remove electrons of host or guest molecules. This type of stimulation does not bring in extraneous redox, so it is a clean and simple method. Additionally, it can be used in biological system for it is actually one type of redox, the most common action type in biomedicine. Therefore, much attention has been attached to voltage-responsive systems. β-cyclodextrin and ferrocene can form inclusion complex by host-guest interaction when mixed together, and this interaction can also be regulated by voltage. Voltage-responsive system based on β-cyclodextrin and ferrocene is the most attractive one, because raw materials are commercially available, biologically compatible and can be modified to polymers easily. This paper investigates the recent work related to this system and summarizes four main parts, from principle, structure and characterization to applications. Moreover, the development and improvement of this system are discussed.

关 键 词：电压刺激 主客体相互作用 Β-环糊精 自组装 可逆调控 

分 类 号：O631[理学—高分子化学] O636[理学—化学]