桂林地区2002例孕妇地中海贫血基因筛查结果分析  

Pregnancy thalassemia gene screening of 2002 cases in Guilin area

作　　者：荆环云[1] 龚蔚蔚[1] 陈洁晶[1] 邹同祥[1] 孙玉峰[1] 谭秋培[1] 吴润强[1] 薛雯[1] 欧明林[1] 

机构地区：[1]中国人民解放军第一八一医院中心实验室广西代谢性疾病研究重点实验室,桂林541002

出　　处：《中国优生与遗传杂志》2013年第11期54-55,共2页Chinese Journal of Birth Health & Heredity

基　　金：广西重点实验室建设项目计划任务书编号:12-071-32

摘　　要：目的统计分析我院2010-2012年产科门诊及住院孕妇地中海贫血基因筛查情况,为本地区地中海防治提供参考依据。方法采用回顾性统计方法,分析我院2002例妊娠妇女筛查结果。结果筛查结果为阳性的患者共341例,占17.03%。其中α-地中海贫血217倒,占10.84%;β-地中海贫血117例,占5.84%;α-地中海贫血复合β-地中海贫血7例,占0.35%。结论本地区地中海贫血发病率高,加强产前筛查,能够减少地中海贫血患儿的出生率,有利于人口素质的提高。Objective： To prevent and control thalassemia, statistical analysis of gene screening of thalassemia was performed in our hospital during 2010 -2012. Methods： The statistical analysis of 2002 cases of pregnant women in our hospital was conducted by retrospective statistical method. Results ： a total of 341 cases was diagnosed as positive （ 17.03% ） ; in these cases, 217 cases was di- agnosed as α- thalassemia （10. 84% ）, 117 cases was diagnosed as β-thalassemia （5.84%）, 7 cases as diagnosed as α and β- thalassemia （0. 35% ）. Conclusions： Guilin is an area with high incidence of thalassemia, prenatal screening may be necessary to re- duce the birth rate of thalassemia and improve population quality.

关 键 词：地中海贫血 产前筛查 阳性率 

分 类 号：R714.254[医药卫生—妇产科学]