青春双歧杆菌口嚼片生产中双歧杆菌存活因素初探  

A STUDY ON SOME INFLUENCE OF SOME FACTORS ON VIABILITY OF BIFIDOBACTERIUM ADOLESCENTIS COMPRISED IN TABLET AS A HEALTHY FOOD

作　　者：朱俊晨[1] 李世敏[1] 

机构地区：[1]深圳职业技术学院生物应用工程系,广东深圳518055

出　　处：《中国微生态学杂志》2000年第6期312-313,共2页Chinese Journal of Microecology

基　　金：深圳市科技局基金资助项目;深科1998(48)号

摘　　要：对生产双歧杆菌口嚼片过程中影响双歧杆菌存活的部分因素进行了研究 ,考察菌龄、干燥制剂的配料中辅应剂成分、水分含量等影响双歧杆菌稳定性的因素。结果表明 ,配料中一定比例的棕榈油、乙基纤维等疏水性填充剂具有保护与稳定双歧杆菌存活的作用 ,在双歧杆菌发酵液中 ,采用对数生长末期的细胞制备的干燥粉料中活菌数及其存活率都较高。产品水分含量以 5 %～ 6 %、充氮包装、存放于低温环境更有利于提高存活率。The influence of some factors on viability of bifidobacterium adolescentis contained in dried preparation was investigated.lt was found that non-hydrophilic matrix substance such as plant oil as well as ethyl-celluose have the effect on enhancement of viability during the store-period,and an incrcased viability of the Bifidobacterium cell comprised in the tablet collected from of cultivation Logarithmic phase.The reason why the viability of bifidobacterium can be influenced by factors such as water content,temperature and matrix substance,as well as,cell age was also discussed to some extent.

关 键 词：微胶囊 双歧杆菌 固定化 

分 类 号：R97[医药卫生—药品] R37[医药卫生—药学]