Decreased frontal lobe function in people with Internet addiction disorder  

作　　者：Jun Liu Fatema Esmail Lingjiang Li Zhifeng Kou Weihui Li Xueping Gao Zhiyuan Wang Changlian Tan Yan Zhang Shunke Zhou 

机构地区：[1]Department of Radiology, Second Xiangya Hosipital, Central South University [2]School of Public Administration, Central South University [3]Wayne State University, Detroit Medical Center [4]Institute of Mental Health, Central South University [5]Hunan Provincial Tumor Hospital

出　　处：《Neural Regeneration Research》2013年第34期3225-3232,共8页中国神经再生研究（英文版）

基　　金：supported by the National Natural Science Foundation of China,No.30830046,30670751,30570695;the National Science and Technology Program of China,No.2007BAI17B02;the National 973 Program of China,No.2009CB918303;the Natural Science Foundation of Hunan Province of China,No.07JJ3042;Department of Public Health of Hunan Province of China,No.B2005048

摘　　要：In our previous studies, we showed that frontal lobe and brainstem functions were abnormal in online game addicts. In this study, 14 students with Internet addiction disorder and 14 matched healthy controls underwent proton-magnetic resonance spectroscopy to measure cerebral function. Results demonstrated that the ratio of N-acetylaspartate to creatine decreased, but the ratio of cho- line-containing compounds to creatine increased in the bilateral frontal lobe white matter in people with Internet addiction disorder. However, these ratios were mostly unaltered in the brainstem, suggesting that frontal lobe function decreases in people with Internet addiction disorder.In our previous studies, we showed that frontal lobe and brainstem functions were abnormal in online game addicts. In this study, 14 students with Internet addiction disorder and 14 matched healthy controls underwent proton-magnetic resonance spectroscopy to measure cerebral function. Results demonstrated that the ratio of N-acetylaspartate to creatine decreased, but the ratio of cho- line-containing compounds to creatine increased in the bilateral frontal lobe white matter in people with Internet addiction disorder. However, these ratios were mostly unaltered in the brainstem, suggesting that frontal lobe function decreases in people with Internet addiction disorder.

关 键 词：neural regeneration Internet addiction disorder internet gaming addiction magnetic resonanceimaging magnetic resonance spectroscopy N-ACETYLASPARTATE choline-containing compounds CREATINE grants-supported paper NEUROREGENERATION 

分 类 号：R749.9[医药卫生—神经病学与精神病学]