纹状体内囊区域内不同面积梗死的病因机制的探讨  

Research on the pathogenesis of striatocapsular territory infarction by a comparative study of clinical and magnetic resonance imaging

作　　者：曲红丽[1,2] 马琪林[1,2] 安星凯[1,2] 鲁丛霞[1,2] 林青[1,2] 黄远亮[1,2] 

机构地区：[1]福建医科大学第一临床学院,厦门361003 [2]厦门大学附属第一医院神经内科

出　　处：《脑与神经疾病杂志》2014年第1期36-39,共4页Journal of Brain and Nervous Diseases

基　　金：福建省科技厅重点项目(2008Y01011292)

摘　　要：目的通过对纹状体内囊区域大小不同面积梗死患者的临床表现与磁共振(MRI)影像特点的对比性分析,探究其发病的病因和机制。方法分析根据发病48h内磁共振弥散加权像(DWI)的结果,确定梗死的部位及大小,按照纹状体内囊梗死(SCI)的影像诊断标准,将58例患者分为(SCI组)26例和(非SCI组)32例。并分别进行临床表现与影像特点的分组对比。结果临床资料显示,两组在NIHSS评分、血压、血糖及CRP等动脉粥样硬化危险因素指标均有显著差异。影像资料显示,病灶分布情况、白质病变在2组对比差异有统计学意义,颈内动脉颅内段、大脑中动脉受累无显著差异。结论 (SCI组)动脉源性或心源性栓塞是主要病因之一,(非SCI组)病因考虑动脉粥样硬化血栓形成。Objective To research the etiology and pathogenesis of striatocapsular territory infarction（ SCI）, the clinical and magnetic resonance imaging （MRI） feature were compared. Methods Fifty-eight patients with striatocapsular territory infarction diagnosed by clinical characteristics and neuroimagings were recruited in this retrospective study, including 26 striatocapsular infarction （SCI） and 32 non-SCI （NSCI）, divided by the diffuse weighing imaging （DWI） in a week MRI, the size of infarct and specific areas, the clinical symptoms and MRI imagings were reviewed to compare their differences.Results The clinical data showed that there was significantly difference between group SCI and group NSCI in NIHSS,blood presure, blood glucose, C-reactive protein（CRP） and so on, except the rate of fibrillation atrial. And the neuroimagings indicated that there were difference in leison distributions and wihite matter lesions, however, the stenosis or occlusion of internal carotid artery （ICA） and middle cerebral artery （MCA） were insignificant. Conclusions The non atherosclerosis risks factors of SCI should be considered. And the causes of lacunar leisons in striatocapsular territory are complicated, mostly relative with atherosclerotic vascular disease.

关 键 词：纹状体内囊区域梗死 临床表现 影像特点 对比研究 发病病因 

分 类 号：R743.32[医药卫生—神经病学与精神病学]