红果参提取物的抗氧化活性研究  

Investigation of Antioxidant Activities of Extracts of Hong Guo Shen

作　　者：陈莉华[1,2] 贺诚志[1] 谭林艳[1] 廖微[1] 王晓静[1] 

机构地区：[1]吉首大学化学化工学院 [2]吉首大学植物资源保护与利用湖南省高校重点实验室,湖南吉首416000

出　　处：《天然产物研究与开发》2014年第2期174-177,201,共5页Natural Product Research and Development

基　　金：科技部科技型中小企业技术创新基金资助项目(10C2621430 2421;11C26414305373);湘西自治州科技计划项目;吉首大学植物资源保护与利用湖南省高校重点实验室开放基金资助项目

摘　　要：超声辅助提取红果参中的抗氧化活性物质并用D-101大孔树脂纯化,以原花青素为指标测定抗氧化活性物质含量,研究了提取物对羟基自由基、超氧阴离子自由基和亚硝酸盐体系的清除作用以及对油脂氧化体系的抑制作用。结果表明:红果参果实提取物表现出了对羟自由基、超氧阴离子自由基及亚硝酸盐的优异的清除能力,对油脂氧化有极好的抑制作用,对自由基的清除率及抗油脂氧化能力与提取物中原花青素质量浓度均呈剂量正相关效应。The antioxidant components of Hong Guo Shen were ultrasonically extracted and purified using D-101 macro- porous resin. The content of the extracts was determined using proanthocyanidins as index. The antioxidant activity of the purified extracts was investigated by testing scavenging effects of · OH, O2 , NO2 and against the peroxidatiou of oils. The results showed that the purified extracts exhibited excellent ability to remove · OH, O2, NO2 and good inhibitory effect to peroxidation of oils. Furthermore＇, the antioxidant activity increased with the increasing of the concentration of extracts.

关 键 词：红果参 原花青素 提取物 抗氧化活性 

分 类 号：R284.2[医药卫生—中药学] R285.2[医药卫生—中医学]