巨脑回畸形与脑室周围白质软化症所致脑性瘫痪的临床分析  

Clinical Features of Cerebral Palsy after Pachygyria and Periventricular Leukomalacia

作　　者：袁俊英[1] 曾宪旭[1] 王遐[1] 

机构地区：[1]郑州大学第三附属医院儿童康复科,河南郑州市450052

出　　处：《中国康复理论与实践》2014年第4期389-391,共3页Chinese Journal of Rehabilitation Theory and Practice

摘　　要：目的探讨巨脑回畸形与脑室周围白质软化症(PVL)导致的脑瘫临床表现、预后等方面的区别与联系。方法回顾性研究巨脑回所致脑瘫15例和PVL所致脑瘫35例,比较种不同原因所致脑瘫在确诊年龄、分型、并发症、粗大运动功能分级(GMFCS)等方面的不同。结果巨脑回畸形组所致脑瘫患儿确诊年龄要显著早于PVL组(P<0.001),GMFCS分级低于PVL组(P<0.05),癫痫发生率高于PVL组(P<0.05),智力显著低于PVL组(P<0.001)。结论巨脑回畸形所致脑瘫整体发育比PVL发育要差,其预后也相对较差。Objective To compare the features of cerebral palsy with pachygyria or periventricular leukomalacia （PVL）. Methods 15 children with pachygyria and 35 children with PVL were included. Their diagnosed age, clinical subtype, complications, Gross Motor Func-tion Classification System （GMFCS） were compared. Results The diagnosed age was significantly younger （P〈0.001）, the GMFCS was lower （P〈0.05）, the incidence rate of epilepsy was higher （P〈0.05）, and the intelligence was significantly lower （P〈0.001） in the pachygyria group than in the PVL group. Conclusion Cerebral palsy children with pachygyria develope worse than that with PVL, as well as their prog-nosis.

关 键 词：脑性瘫痪 巨脑回畸形 脑室周围白质软化症 

分 类 号：R742.3[医药卫生—神经病学与精神病学]