MAG-1和mTOR生物学功能研究进展  

The research progress of MAG- 1 and mTOR biological function

作　　者：杨云琳[1,2] 杨娟[1,2] 任明智[1,2] 赵长林[1,2] 

机构地区：[1]大连大学附属新华医院肿瘤科 [2]大连大学肿瘤研究所,辽宁大连116021

出　　处：《现代肿瘤医学》2014年第3期723-725,共3页Journal of Modern Oncology

摘　　要：PI3K/Akt/mTOR信号传导通路是细胞内重要的信号传导通路之一,mTOR是该通路的焦点,其上游和下游效应分子的不同活化状态对细胞的增殖、运动等生物学功能发挥重要作用。MAG-1是近年来新发现的mTOR上游效应分子,通过mTOR信号传导通路发挥生物学功能。本文就MAG-1和mTOR生物学功能研究进展作一综述。PI3K/Akt/mTOR signaling pathway is one of the important signaling pathways in cells, mTOR has be- come the focus of the pathway,the different activation condition of upstream and downstream molecules of mTOR play important biological role on cell proliferation,sports. MAC - 1 is discovered in recent years,it is a new molecule up mTOR and through the roTOR signaling pathways play a biological function, in this paper,we reviewed research pro- gress of MAC - 1 and roTOR biological function.

关 键 词：MAG-1 MTOR 研究进展 

分 类 号：R730[医药卫生—肿瘤]