表皮生长因子受体3在乳腺癌中的研究进展  

Research progresses of ErbB3/HER3 in breast cancer

作　　者：阮姝琴[1] 王善伟[2] 杨志祥[1] 

机构地区：[1]重庆市中山医院肿瘤血液科,重庆400012 [2]西安医学院病理教研室,陕西西安710021

出　　处：《现代肿瘤医学》2014年第5期1200-1202,共3页Journal of Modern Oncology

基　　金：陕西省教育厅自然科学研究项目(编号:12JK0709);重庆市渝中区科技计划项目(编号:20130144)

摘　　要：表皮因子受体3(ErbB3/HER3)是表皮生长因子跨膜受体家族的成员之一。近年来证实ErbB3/HER3与乳腺癌的发病、复发转移、化疗以及内分泌治疗的疗效密切相关,已成为非常有前景的治疗候选靶点。本文简要综述近年来ErbB3/HER3在乳腺癌中的研究进展。ErbB3 / eER3 is one member of ErbBs family. In recent years,it has been confirmed that ErbB3 / eER3 was involved in the Pathogenesis,recurrence,metastasis and the curative effect of chemotheraPy and endocrine theraPy in breast cancer. ErbB3 / eER3 has been becoming a Promising new target for breast cancer treatments. This PaPer is going to summarize the research Progress of ErbB3 / eER3 in breast cancer.

关 键 词：ErbB3/HER3 乳腺癌 EGFR 

分 类 号：R737.9[医药卫生—肿瘤]