婴幼儿配方奶粉中邻苯二甲酸酯的固相萃取净化-气相色谱-质谱法测定  

Determination of phthalates in infant formula by gas chromatography-mass spectrometry coupled with solid phase extraction

作　　者：苗宏健[1] 鲁杰[1] 梁丽娜 赵云峰[1] 

机构地区：[1]国家食品安全风险评估中心卫生部食品安全风险评估重点实验室,北京100021 [2]赛默飞世尔科技(中国)有限公司,北京100044

出　　处：《中国乳品工业》2014年第5期54-57,共4页China Dairy Industry

基　　金：863课题(2012AA101603)动植物源食品中内源有害物精准检测技术;十二五科技支撑(2011BAK10B05-02)食品接触材料中有害物质迁移量关键检测技术研究

摘　　要：建立婴幼儿配方奶粉中邻苯二甲酸酯（PAEs）固相萃取净化,气相色谱-质谱法测定的方法。样品加入同位素内标后,以乙腈提取,PSA/Silica固相萃取柱净化,气相色谱-质谱法检测,内标法定量。结果表明：该方法对婴幼儿配方奶粉的16种PAEs定量限为50～100μg/kg,加标回收率在74%～124%之间,RSD在0.78%～7.1%之间。该方法简便快捷,定量准确,重现性好,适用于高通量检测婴幼儿配方奶粉中PAEs质量分数。The determination method of phthalates（PAEs） in infant formula by gas chromatography-mass spectrometry coupled with solid phase extraction was developed. The samples were spiked with isotope internal standards and then extracted with acetonitrile and cleaned up with PSA/Silica solid phase extraction. Finally the cleaned-up samples were detected by gas chromatography-mass spectrometry and quantified by internal standard method. The clean-up procedure was effective in the determination of phthalates in infant formula. The limits of quantification for PAEs were 50～100 μg/kg. The recoveries of this method were between 74%～124% with RSD of 0.78%～7.1%. The method was simple,efficient and suitable for high throughput determination of PAEs in infant formula.

关 键 词：婴幼儿配方奶粉 邻苯二甲酸酯 固相萃取法 气相色谱-质谱法 

分 类 号：TS252.7[轻工技术与工程—农产品加工及贮藏工程]