2005 -2012 年辽阳市新生儿疾病筛查情况分析  

Analysis on neonatal screening in Liaoyang city from 2005 to 2012

作　　者：赵昕[1] 赵宏凯[1] 

机构地区：[1]辽宁省辽阳市妇幼保健所,111000

出　　处：《中国妇幼保健》2014年第18期2909-2910,共2页Maternal and Child Health Care of China

摘　　要：目的分析辽阳市2005～2012年新生儿疾病筛查情况，了解新生儿先天性甲状性功能减退症（CH）和苯丙酮尿症（PKU）的发病率，为进一步开展筛查工作提供依据。方法：新生儿出生72 h充分哺乳后采集足跟血滴于滤纸片，进行筛查。结果：2005，2012年辽阳市共筛查新生儿96 619例，确诊新生儿CH 33例，CH的发病率为1：2 928；确诊PKU 11例，PKU的发病率为1：8 784。新生儿疾病筛查率呈逐年上升的趋势。结论：新生儿疾病筛查是CH、PKU早期诊断的有效措施，对cH、PKU患儿在症状出现前进行早期干预，可以保障患儿体格和智力的正常发育。加强新生儿疾病筛查工作质量，有效提高辽阳市新生儿疾病筛查的覆盖率，降低漏诊率，减少弱智儿童的发病率，对提高出生人口素质起着积极的作用。ObjectiveTo analyze the screening condition of neonatal diseases in Liaoyang city from 2005 to 2012, understand the inci-dence rates of congenital hypothyroidism （CH） and phenylketonuria （PKU）, and provide a basis for further conducting neonatal screening.Methods：Blood samples were collected from the heel of neonates at 72 hours after fully breastfeeding for screening. Results：A total of 96 619neonates were screened in Liaoyang city from 2005 to 2012, 33 neonates were diagnosed as CH definitely, the incidence rate of CH was 1 ： 2928 ; 11 neonates were diagnosed as PKU definitely, the incidence rate of PKU was 1： 8 784 ; the screening rate of neonatal diseases showed anincreasing trend year by year. Conclusion： Neonatal screening is an effective measure for early diagnosis of CH and PKU. Early intervention isneeded for those neonates before appearance of CH and PKU symptoms to ensure normal physical and intelligent development of neonates. Thequality of neonatal screening should be enhanced to effectively improve the coverage rate of neonatal screening in Liaoyang city, reduce misseddiagnostic rate and the morbidity of mentally retarded children, which plays an active role in improving quality of birth population.

关 键 词：新生儿疾病筛查 先天性甲状腺功能减退症 苯丙酮尿症 

分 类 号：R722[医药卫生—儿科]