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机构地区:[1]广州中医药大学第一附属医院实验中心,广东广州510405 [2]暨南大学医学院,广东广州510632
出 处:《食品工业科技》2014年第13期337-340,共4页Science and Technology of Food Industry
摘 要:考察冲锋壹号果味咖啡饮料的壮阳作用及耐缺氧能力,为该饮料的进一步研究提供实验依据。通过对去势雄性大鼠和正常雄性大鼠灌胃给药,观察其扑捉潜伏期、扑捉次数、射精次数、扑捉动物例数和射精动物例数,测定血清睾酮含量,取前列腺、精囊腺和提肛肌测定湿重,计算其脏器指数;小鼠连续灌胃给药,观察小鼠在常压缺氧试验、亚硝酸钠中毒存活试验、急性脑缺血性缺氧存活试验中耐缺氧的能力。结果:冲锋壹号果味咖啡饮料高剂量组对去势雄性大鼠能缩短扑捉潜伏期(p<0.05),增加扑捉次数(p<0.05)和射精次数(p<0.05);高、中剂量组均能延长小鼠常压耐缺氧潜伏期(p<0.05),延长急性脑缺血性缺氧后小鼠的存活时间(p<0.001,p<0.05)。冲锋壹号果味咖啡饮料具有壮阳作用及耐缺氧功能。The tenifying Yang and anti- anoxia effects of Chongfengyihao fruit coffee drink (CFCD) was studied toprovide evidences in pharmacodynamics experiment for further investigation.Orchidectomized and normal malerats were administered with CFCD by gavage, and capture incubation period, capture times, ejaculation times,capture female rat cases and ejaculation male rat cases were observed. Meanwhile the content of testosterone inserum of rats was measured.Seminal vesicle, prostate and anal muscle were weighted and the viscera index werecalculated; Mouse were administered with CFCD by gavage, normal pressure hypoxia test, the survival time ofsodium nitrite poisoning, and acute cerebral ischemic anoxic survival test were employed to monitor CFDC's onenhancing anoxia ability.Results indicated that CFCD at high dose shortened capture incubation period( p 〈 0.05),increased capture times( p 〈 0.05 ) and ejaculation times ( p 〈 0.05 ) in orchidectomized male rats; wihle CFCD atboth high and middle dose prolonged the latent period of normal pressure hypoxia(p 〈 0.05)and the survival timeof acute cerebral ischemic anoxic(p 〈0.001 ,p 〈0.05).This research suggested that CFCD had tonifying Yang andanti-anoxia effects.
分 类 号:TS201.4[轻工技术与工程—食品科学]
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