胃癌患者胃粘膜无芽胞厌氧菌分析及药物敏感试验  

STUDIES ON GASTRIC NON-SPORE-FORMING ANAEROBIC CHANGES AND DRUG SENSITIVITY TEST IN PATIENTS WITH GASTRIC CANCER

作　　者：张博芬[1] 谭颖慧[1] 朱晓敏[1] 刘文新[1] 敦玉娥 王宇[3] 张芬芬[3] 

机构地区：[1]沈阳医学院微生物教研室,沈阳110031 [2]沈阳市铁西区第二医院,沈阳110024 [3]辽宁大学生命科学学院,沈阳110033

出　　处：《中国微生态学杂志》2001年第1期44-45,53,共3页Chinese Journal of Microecology

摘　　要：对 98例具有消化不良症状的患者做胃镜检查 ,取胃粘膜组织进行细菌分离培养 ,结果表明 ,不同的消化道疾病 ,胃粘膜微生物群均发生不同的改变 ,其中胃癌患者改变最明显 ,胃内微生物检出率最高 ,无芽胞厌氧菌检出率 87.88% ( 2 9/ 33) ,其中产亚硝酸优杆菌检出率为 5 7.6 0 % ( 19/ 33) ,硝酸盐还原试验阳性菌株占 72 .70 % ( 2 4/ 33)。这些细菌与胃癌的关系有待深入研究。对 19株产亚硝酸优杆菌做药物敏感试验 ,结果显示 ,该菌对青霉素类药物均耐药 ,对氯霉素 ,红霉素 。cases of patients with dyspepain were examined by gastroscope and gastricmucus was took out for isolation and cultivation of microorganism The resalts showed that microbiota in gastric mucus varied widely over different gastric diseases The change of microbiota of patient with gastric cancer was much remarkable, for the detecting rate of gastric microorganism was the highest The detecting rate of non-spore-forming anaerobic was 87 88%(29/33) in the patients with gastric cancer The detecting rate of E nitritogenes was 57 60%(19/33) Reductive test of the nitrous salt positive strain was about 72 70%(24/33) The connection between these bacteria and gastric cancer is needed for further study 19 strains E nitritogenes were sensitivity to chloramsaar, erythromycin, gentamycin; were resistance to penicilin by the drug sensitivity test

关 键 词：胃癌 微生物群 产亚硝酸优杆菌 药物敏感试验 胃粘膜 

分 类 号：R735.2[医药卫生—肿瘤] R378[医药卫生—临床医学]