产氨短杆菌GMA-1112利用味精母液发酵生产肌苷  

Inosine Production from Glutamic Acid Mother Liquid by Brevibacterium ammoniagenes

作　　者：施庆珊[1] 李良秋[1] 林小平[1] 邱玉棠[1] 

机构地区：[1]广东省微生物研究所,广州510070

出　　处：《氨基酸和生物资源》2001年第1期21-23,共3页Amino Acids & Biotic Resources

基　　金：广州市自然科学基金

摘　　要：通过亚硝基胍或60 Coγ辐照等选育一株产氨短杆菌GMA 1 1 1 2 (Ade +Gua +VB1 +8 AGr+SGr+6 MPr) ,能以味精母液代替传统肌苷发酵添加酵母粉作为有机营养物 ,进行肌苷发酵 ,平均产肌苷率 2 5.4 0 g/L。具有降低发酵成本、提高产肌苷率等优点。An inosine-producing mutant of Brevibacterium ammoniagenes GMA-1112 (Ade +Gua +VB 1 +8 AG r+6 MPr) was bred with the treatment of N-methyl-N-nitro-N-nitrosoguanidine (NTG) and 60 Cor radiation etc. The inosine fermentation utilizing glutamic acid mother liquid as an organic nutrient instead of yeast powder was optimized. It was found that the strain could accumulate 25.40g/L of inosine in average.

关 键 词：产氨短杆菌 肌苷 味精母液 发酵 

分 类 号：TQ464.3[化学工程—制药化工] TQ929[轻工技术与工程—发酵工程]