神经—肌肉继发性兴奋的时间总和——“循经感传”机制研究(Ⅱ)  

Temporal Summation of Secondary Excitation in Nerve-Muscle——Study on Mechanism of Propagated Sensation Along Meridian(Ⅱ)

作　　者：朱兵[1] 贲卉[1] 徐卫东[1] 荣培晶[1] 李宇清[1] 

机构地区：[1]中国中医研究院针灸研究所,北京100700

出　　处：《中国针灸》2001年第5期291-293,共3页Chinese Acupuncture & Moxibustion

基　　金：国家攀登计划项目;国家自然科学基金资助项目

摘　　要：实验用离体的坐骨神经—腓肠肌组织和后肢的坐骨神经及其分支、腓肠肌、趾长伸肌—胫前肌。结果证明 ,刺激坐骨神经引起的腓肠肌纤维兴奋过程中的去极化电位形成的综合电流能刺激穿越该肌的神经 ,引起该神经支配的肌肉继发性兴奋反应。将引起继发性神经—肌肉反应的刺激电流降至阈值强度 ,连续 2个或更多的脉冲刺激 (间隔在 10～ 10 0 0ms之间 )可发生时间总和的激活反应。这种时间总和效应有助于解释沿经脉感觉慢速迁移现象。Purpose To investigate the secondary excitation of electrical activity of the muscle on the contiguous nerve.Methods Experiments were performed on isolated and in situ nerve-muscle preparation of rats.Results Action potential of muscle is capable of producing excitation of the nerve adjacent to the muscle and inducing transmission of excitation from the muscle to the nerve.When electrical current of stimulation inducing nerve-muscle response was lowered to the threshold intensity,continuous two or more impulses given in an interval of 10～1000ms could produce secondary excitation of temporal summation.Conclusion The temporal summation effect of secondary excitation can explain the phenomenon of sensation slow propagating along meridians in TCM.

关 键 词：神经-肌肉接头 针灸效应 电生理学 循经感传 肌收缩 生理学 

分 类 号：R224.1[医药卫生—中医基础理论]