HSK患者外周血T-淋巴细胞亚群与SIL-2R关系的研究  被引量:5

Relationship between Tlymphocyte subpopulations and SIL2R in cases of recurrent herpes simplex keratitis

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作  者:张华[1,2] 宋宏文[1,2] 迟福昌 王志安[1,2] 郭绒霞 孙乃学[1,2] 

机构地区:[1]山东省济宁市第一人民医院 [2]西安医科大学第二附属医院眼科

出  处:《眼科研究》1998年第1期43-45,共3页Chinese Ophthalmic Research

摘  要:目的研究复发性单纯疱疹性角膜炎(herpessimplexkeratitis,HSK)患者外周血T-淋巴细胞亚群变化与血清可溶性白细胞介素-2受体(solubleinterleukin-2receptor,SIL-2R)水平的关系。方法测定了30例复发性HSK患者外周血T-淋巴细胞亚群,同时检测血清SIL-2R的水平并与25例健康人做对照。结果复发性单纯疱疹性角膜炎患者CD3、CD4/CD8均值与正常对照组相比明显降低;血清SIL-2R与对照组比较显著增高。结论复发性HSK患者体内免疫功能低下,SIL-2R水平升高可能是其原因之一,这也为免疫治疗提供了一定依据。ObjectiveTo study the relationship between Tlymphocyte subpopulations and soluble interleukin2 receptor(SIL2R)in patients with recurrent herpes simplex keratitis (HSK).MethodsTlymphocyte subpopulations in peripheral blood of SIL2R were detected in 30 cases of recurrent HSK and 25 healthy controls.ResultsThere were decreased elevations of CD3,CD4/CD8,when compared to healthy controls;there were also significant elevations of serums SIL2R when compared to healthy controls.ConclusionThe immune function of recurrent HSK is lower than that of healthy controls.While the level of SIL2R is higher.These discoveries can provide a foundation for immunotherapy.

关 键 词:单纯疱疹I型 T-淋巴细胞亚群 可溶性白细胞介素-2受体 SIL-2R 角膜炎 HSK 

分 类 号:R772.21[医药卫生—眼科]

 

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