体部较大肿瘤X线立体定向放射手术与适形治疗之比较  

Comparison of stereotactic radiosurgery(SRS) and conformal radiotion therapy(CRT) for body tumors

作　　者：金同梅[1] 王庆夕[1] 孙仲藩[2] 

机构地区：[1]连云港市第一人民医院放疗科,连云港222002 [2]中国人民解放军空军总医院放疗科,北京100036

出　　处：《陕西肿瘤医学》2000年第4期215-217,共3页ShanXi Oncology Medicine

摘　　要：目的　评价体部X线立定定向放射手术 (stereotacticradiosurgey ,SRS ,俗称X 刀[1] )与适形放射治疗 (conformalradiationtherapy ,CRT)两种照射方法对于治疗直径大于 5cm肿瘤的利弊。 方法　对每一病例分别进行X线立体定向及适形两种治疗计划的设计 ,作出DVH图。结果　两种照射方法对靶区的包绕均符合临床需要 ,但立体定向放疗组靶区内部剂量不均匀、有热点 ,虽然对正常组织照射区域小 ,但有局部较高剂量区存在。结论　两种方法各有利弊 ,但适形治疗对于减少治疗中的不良反应与并发症 ,明显优于前者 ,对于直径大于 7cm的肿瘤应优先选用适形治疗的照射方法。Objective To compare advantages and disadvantages of stereotactic radiosurgery(SRS) and conformal radiotion therapy(CRT) for body tumors of diameter≥5cm. Methods 21 patients were adopted therapy plan of SRS and CRT with dose-volume histogram(DVH). Results Both SRS and CRT meet the clinical need of enwrapping target volume. Although normal tissue received small radiation field accompanying with local high dosage in SRS, target volume had heterogenous dosage and hot spot. Conclusions CRT had fewer bad reaction and complication. CRT was preferntial therapy plan for body tumors of diameter≥7cm.

关 键 词：X线立体定向放射手术 适形治疗 肿瘤 比较 

分 类 号：R730.55[医药卫生—肿瘤]