4～5岁儿童核黄素营养状况评价指标探讨  

A STUDY ON THE EVALUATION OF VITAMIN B2 NUTRITIONAL STATUS IN CHILDREN

作　　者：柳启沛[1] 陈文根[1] 吴岩玮[2] 王建强[2] 胡正飞[2] 朱芳[2] 

机构地区：[1]上海医科大学公共卫生学院营养与食品卫生学教研室 [2]上海医科大学

出　　处：《上海医科大学学报》1991年第6期456-460,共5页Journal of Fudan University(Medical Science)

摘　　要：以40名4～5岁全托健康儿童为受试对象,在数次尿样测定中发现1、4及24h尿肌酐的平均排泄量各自不等,且变异较大;还发现无论核黄素(VB_2)摄入充足与否,空腹尿、任意尿中VB_2/肌酐与24h尿中VB_2量及其VB_2/肌酐之相关结果也不一致,在同一个体,各不同尿样的VB_2/肌酐也不稳定。提示以任意一次尿样VB_2/肌酐来评价机体VB_2营养状况都必须十分慎重。 在VB_2摄入充足或不足时,儿童以2.5mg进行VB_2 4h负荷试验的敏感性,均高于以5.0mg为负荷量的结果,且前者与24h尿VB_2排泄量呈现相关。故认为儿童VB_2 4h负荷试验,以2.5mg为负荷量较稳妥。A study in 40 healthy children aged from 4-5 years old showed that the-urine creatine/hour levels were different in 1-hour, 4-hour or 24-hour urine samples either in individual or in collective calculation. Whether the VB 2 intake is sufficient or not, VB 2/creatine ratios of morning, random urine samples showed no consistent correlation with VB 2/creatine and VB 2 of 24-hours sample. VB 2/creatine was also inconsistent in different urine samples by individual calculation. The results suggested that it might not be reasonable to use VB 2/creatine of random urine in the evaluation of VB2 nutritional status.Whether the VB2 intake is sufficient or not, using 2.5mg VB 2 as the loading dosage of a 4-hour loading test in children was more sensitive than using 5 mg VB 2. There was a significant correlation between the VB 2 excretion in 24-hour urine and that in 4-hour loading test urine using 2.5mg VB2, but not that so when using 5mg VB2.The results recommend 2.5mg VB2 as the loading dosage in the 4 hour loading test of VB2 in children.

关 键 词：尿肌酐 尿 儿童 核黄素 

分 类 号：R197[医药卫生—卫生事业管理]