醒后卒中的临床特征、影像学特征和发病机制  

Clinical features,imaging features and pathogenesis of wake-up stroke

作　　者：李光硕 毕国荣[1] Li Guangshuo;Bi Guorong(Department of Neurology,Shengjing Hospital of China MediCal University,Shenyang 110072,China)

机构地区：[1]中国医科大学附属盛京医院神经内科,沈阳110072

出　　处：《国际脑血管病杂志》2018年第11期838-846,共9页International Journal of Cerebrovascular Diseases

摘　　要：尽管无明确的定义,但多数文献倾向于将入睡前无明显异常而起床后发现神经功能缺损症状的卒中归类为醒后卒中(wake-up stroke,WUS),约占全部卒中病例的15%~30%,目前对其发病机制知之甚少.研究显示,WUS的危险因素、临床特征,特别是初始严重程度和转归方面与非WUS无明显差异.目前的研究重点主要是其静脉溶栓和血管内治疗的获益及风险.Although there is no definite definition,the stroke that has no abnormalities before going to sleep and finds a neurological deficit after waking up are classified as wake-up strokes (WUS)in most of the literature.WUS account for 15%-30%of all stroke cases,and little is known about its pathogenesis.Studies have shown that there is no significant difference in risk factors,clinical features,especially initial severity and outcome between WUS and non-WUS.The current research focuses on the benefits and risks of intravenous thrombolysis and endovascular treatment in WUS.

关 键 词：卒中 脑缺血 弥散磁共振成像 磁共振血管造影术 灌注成像 时间因素 

分 类 号：R743.3[医药卫生—神经病学与精神病学]