Applying comprehensive histologic assessment and genetic testing to synchronous multifocal lung adenocarcinomas and further survival analysis  

作　　者：Fei Xiao Zhen-Rong Zhang Xiao-Wei Wang De-Ruo Liu Yong-Qing GUO Bin Shi Zhi-Yi Song Chao-Yang Liang 

机构地区：[1]National Clinical Research Center for Respiratory Diseases,Center for Respiratory Diseases,Department of Thoracic Surgery,China-Japan Friendship Hospital,Beijing 100029,China [2]Department of Pathology,China-Japan Friendship Hospital,Beijing 100029,China

出　　处：《Chinese Medical Journal》2019年第2期227-231,共5页中华医学杂志（英文版）

摘　　要：To the Editor:The differentiation of multiple primary lung adenocarcinomas (MPLAs) from metastases is important to allow for proper clinical management and prognostic prediction.The current revised diagnostic criteria for MPLAs proposed by the American College of Chest Physicians (ACCP) have been commonly applied since 2003.[1] However, it remains technically challenging to determine whether 2 or more lung adenocarcinomas from the same patient are homologous.Various approaches and algorithms including gene mutation analysis addressing this problem have been described.[2,3] Here, we present a cohort of 45 patients with synchronous multifocal lung adenocarcinomas.

关 键 词：DIFFERENTIATION ADENOCARCINOMAS PROGNOSTIC prediction 

分 类 号：R[医药卫生]