胃癌患者焦虑/抑郁及其与生命意义关系的研究  

Correlation between anxiety/depression and life meaning in patients with gastric cancer

作　　者：李秀[1] 姚霜[1] 韦永明 袁慧[1] LI Xiu;YAO Shuang;WEI Yong-ming;YUAN Hui(Department of Psychology,Wannan Medical College,Wuhu 241000,China;Department of Oncology,Wubu Second People's Hospital,Wuhu 241000,China)

机构地区：[1]皖南医学院心理学教研室,安徽芜湖241000 [2]芜湖市第二人民医院肿瘤科,安徽芜湖241000

出　　处：《中华疾病控制杂志》2018年第3期240-243,共4页Chinese Journal of Disease Control & Prevention

基　　金：安徽省教育厅人文社会科学重点研究项目(sk2016A0956);皖南医学院博士科研基金启动项目(WK2014RC04)

摘　　要：目的调查胃癌患者焦虑/抑郁水平,探讨其与生命意义(meaning of life,MOL)之间的关系。方法采用病例对照的研究方法,对165例25~83岁于三级甲等医院肿瘤科住院的胃癌患者和同期165例门诊确诊为浅表性胃炎患者,用心理弹性量表、MOL量表、医院焦虑抑郁量表、一般资料调查表进行调查。结果胃癌患者焦虑/抑郁水平较高,MOL水平较低;MOL和胃癌患者焦虑/抑郁呈负相关(r=-0.291,P<0.001);MOL在心理弹性和胃癌患者焦虑/抑郁之间起中介作用。结论 MOL的重构可以增强患者心理弹性,对胃癌患者焦虑、抑郁情绪有预测作用。这一发现有助于为胃癌患者焦虑、抑郁的预防及临床研究提供新的思路及参考依据。Objective To investigate anxiety/depression in patients with gastric cancer and their relationship with meaning of life( MOL). Methods We enrolled 165 inpatients( aged 25-83 years) with gastric cancer in the department of oncology from two tertiary hospitals. At the same time,we enrolled 165 patients diagnosed as superficial gastritis in outpatient department. We assessed the patients using the resilience scale,meaning in life questionnaire,hospital anxiety and depression scale,and the general data questionnaire. Results The anxiety/depression levels of gastric cancer patients were higher,and the life meaning was lower;MOL was negatively correlated with anxiety/depression in patients with gastric cancer( r =-0. 291,P < 0. 001). MOL played a mediating role between resilience and anxiety/depression in gastric cancer patients. Conclusions The reconstruction of MOL can enhance the resilience of patients and predict the anxiety/depression of patients with gastric cancer. This may provide new insights into clinical research and interventions for anxiety/depression in patients with gastric cancer.

关 键 词：胃肿瘤 焦虑 抑郁 心理 弹性 生命意义 

分 类 号：R735.2[医药卫生—肿瘤] R749.72[医药卫生—临床医学]