氯霉素葡萄糖注射液的细菌内毒素定量检测  

Quantitative Detection of Endotoxin in Chloramphenicol Glucose Injection

作　　者：邓鸣[1] 张素芬[1] 潘静[1] 

机构地区：[1]中国人民解放军白求恩国际和平医院,河北石家庄050082

出　　处：《中国药业》2002年第3期51-52,共2页China Pharmaceuticals

摘　　要：目的：探讨动态浊度法测定氯霉素葡萄糖注射液细菌内毒素的可行性。方法：用细菌内毒素测定仪考察氯霉素葡萄糖注射液对细菌内毒素的干扰。结果：氯霉素葡萄糖注射液４倍稀释液对细菌内毒素无干扰作用。结论：可用动态浊度法取代热原检查法测定氯霉素葡萄糖注射液中的细菌内毒素。Objective: Discuss the feasibility of dynamic turbidity method to determine the endotoxin in chlorampheni- col glucose injection. Method: Determines the interference of chloramphenicol glucose injection to endotoxin with the Endotoxin Analyzer. Results: 4 times dilute of Chloramphenicol glucose injection has no interfering effect on endo- toxin. Conclusion: Dynamic turbidity method can replace pyrogen assay to determine endotoxin in chloramphenicol glucose injection.

关 键 词：氯霉素葡萄糖注射液 动态浊度法 鲎试剂 细菌内毒素 

分 类 号：R927.12[医药卫生—药学]