Lymph node metastasis and lymphadenectomy of resectable adenocarcinoma of the esophagogastric junction  

作　　者：Xin-Zu Chen Wei-Han Zhang Jian-Kun Hu 

机构地区：[1]Department of Gastrointestinal Surgery,West China Hospital,Sichuan University

出　　处：《Chinese Journal of Cancer Research》2014年第3期237-242,共6页中国癌症研究（英文版）

基　　金：National Natural Science Foundation of China (No. 81372344 and 81301866);New Century Excellent Talents in University support program, Ministry of Education of China (2012SCU-NCET-11-0343)

摘　　要：Based on Siewert classification, adenocarcinomas of the esophagogastric junction （AEGs） have different behaviors of perigastric-mediastinal nodal metastasis. Siewert type I AEGs have higher incidence of mediastinal nodal metastasis than those of type H or III, especially at middle-upper mediastinum. With regard to the necessity of mediastinal lymphadenectomy, theoretically, transthoracic esophagogastrectomy with complete mediastinal lymphadenectomy is suggested for Siewert type I AEGs, while transhiatal total gastrectomy with lower mediastinal and D2 perigastric lymphadenectomy is a standard surgery for type II-III AEGs. Nevertheless, the mediastinal nodal metastasis is an independent factor of poor prognosis for any type of AEG.Based on Siewert classification, adenocarcinomas of the esophagogastric junction （AEGs） have different behaviors of perigastric-mediastinal nodal metastasis. Siewert type I AEGs have higher incidence of mediastinal nodal metastasis than those of type H or III, especially at middle-upper mediastinum. With regard to the necessity of mediastinal lymphadenectomy, theoretically, transthoracic esophagogastrectomy with complete mediastinal lymphadenectomy is suggested for Siewert type I AEGs, while transhiatal total gastrectomy with lower mediastinal and D2 perigastric lymphadenectomy is a standard surgery for type II-III AEGs. Nevertheless, the mediastinal nodal metastasis is an independent factor of poor prognosis for any type of AEG.

关 键 词：Adenocarcinomas of the esophagogastric junction （AEGs） SURGERY lymph node METASTASIS LYMPHADENECTOMY 

分 类 号：R735.2[医药卫生—肿瘤]