综合营养干预对消化道肿瘤化疗病人营养状况及生存质量的影响  

Influence of comprehensive nutrition intervention on quality of life and nutritional status of patients with gastrointestinal tumor receiving chemotherapy

作　　者：骆海燕[1] 姚红梅 郑亚华 李美珍[1] 马腹婵[1] 吴珊珊[1] 

机构地区：[1]宁波卫生职业技术学院 [2]浙江省宁波市鄞州人民医院 [3]浙江省宁波市李惠利医院

出　　处：《护理研究（下旬版）》2014年第8期2961-2964,共4页Chinese Nursing Researsh

基　　金：浙江省教育厅科研项目;编号:Y201122073

摘　　要：[目的]探讨综合营养干预对消化道肿瘤病人化疗不同时间点的营养状况和生存质量的影响,为临床护理改善其营养状况、提高其生存质量提供实践依据。[方法]采用便利抽样法选取符合入选标准病人84例,用随机数字法分为对照组和干预组,每组42例,对照组实施肿瘤化疗护理常规,干预组在此基础上实施综合营养干预措施。分别在化疗不同时间点(化疗前、化疗中、化疗后)用主观全面营养状态评价量表和癌症病人生存质量评价量表第3版中文版对病人营养状况和生存质量的变化进行调查,分析综合营养干预的效果。[结果]随着化疗的进行,干预组营养状况和生存质量显著优于对照组,差异有统计学意义(P<0.05);经重复测量方差分析,不同时间及组间评分比较,差异有统计学意义(P<0.05)。[结论]消化道肿瘤病人化疗期间在常规肿瘤化疗护理基础上实施有效的综合营养干预,可以改善病人营养状况,提高病人的生存质量。Objective：Toprobeintotheinfluenceofcomprehensivenutri-tion intervention on quality of life and nutritional status of patients with gastrointestinal tumor receiving chemotherapy at different time points,so as to provide a practical basis for clinical care workers to improve the pa-tients′nutritional status and their quality of life.Methods：The convenience sampling method was used to select 84 cases of patients who met the inclu-sion criteria,and they were randomly divided into control group and experi-mental group by using random number method,42 cases in each;patients in control group implemented nursing routine of tumor chemotherapy,pa-tients in experimental group received comprehensive nutrition interventions on this basis.The nutritional status and their quality of life were surveyed by using SGA and EORTC QLQ C30（version3.0）at chemotherapy differ-ent time points （before chemotherapy,during and after chemotherapy）, then to analyze the effect of comprehensive nutrition interventions.Re-sults：During chemotherapy,the nutritional status and quality of life in in-tervention group were significantly better than that in control group,and the difference was statistically significant （P〈0.05 ）.After repetitive measurement and analysis of variance,the difference was statistically sig-nificant between different times and groups （P〈0.05 ）.Conclusion：The comprehensive nutrition interventions on the basis of chemotherapy routine care can improve the nutritional status and quality of life of patients with gastrointestinal tumor chemotherapy.

关 键 词：消化道肿瘤 化疗 综合营养干预 生存质量 

分 类 号：R473.73[医药卫生—护理学]