果胶/壳聚糖抗菌膜结构及性能分析  

Analysis on the structure and practice properties of pectin/chitosan composite membrane

作　　者：丁克毅[1] 王虹霞[1] 刘军[1] 王洁雪[2] 

机构地区：[1]西南民族大学化学与环境保护工程学院,四川成都610041 [2]成都师范学院化学与应用化学系,四川成都611113

出　　处：《西南民族大学学报（自然科学版）》2014年第5期680-685,636,共6页Journal of Southwest Minzu University(Natural Science Edition)

基　　金：四川省科技创新苗子工程资助项目"用果胶替代明胶制备药用胶囊膜材料"(项目编号:2012CZ008);西南民族大学研究生创新科研重点项目"用果胶替代明胶制备药用胶囊膜材料"(项目编号:CX2013SZ14)

摘　　要：采用溶液共混法制备了不同质量比例的果胶/壳聚糖复合膜,用IR、XRD表征其结构,并测试了复合膜的溶胀度、水蒸气透过率、透光率、体外降解和抗菌性等性能.结果表明:果胶和壳聚糖分子间有很好的相容性并发生了一定的相互作用;当二者质量比例为1:1时,复合膜的水蒸气透过率最低、透气性较小,溶胀度达到487%,并且能够保持良好的体外降解性和抗菌性.Solution blending method was applied to prepare pectin/chitosan（PEC/CS） composite membrane with different quality proportions, IR and XRD were adopted to describe the structure of membrane, and the swelling behavior, water vapor permeability（WAP）, light transmittance, in vitro degradation and antimicrobial properties of membrane were measured. The results indicated that, pectin and chitosan have a good compatibility, and that physical-chemical interaction would take place between them during the blending process. The obtained membrane had the lowest water vapor transmittance when the quality ratio was 1：1, and its air permeability was relatively low also, its swelling degree reached 487%, and the composite membrane kept a good in vitro degradation and antimicrobial properties.degradation and antimicrobial properties.

关 键 词：果胶 壳聚糖 复合膜 抗菌性 

分 类 号：R318.08[医药卫生—生物医学工程]