富含单不饱和脂肪酸的坚果对高脂血症患者血脂水平的影响  

Study on Effect of Nut Rich in Monounsaturated Fatty Acid on Serum Lipids in Hyperlipidemia Patients

作　　者：肖颖[1] 王军波[1] 闫少芳[1] 梁学军[1] 唐仪[1] 刘毅[1] 

机构地区：[1]北京大学公共卫生学院营养与食品卫生学系,北京100083

出　　处：《中国公共卫生》2002年第8期931-932,共2页Chinese Journal of Public Health

摘　　要：目的　观察富含单不饱和脂肪酸的坚果—美国大杏仁对高脂血症患者的降血脂作用。方法　以 85名高脂血症患者为受试者 ,每天服用 75 g大杏仁 ,连续服用 4周 ,在停止服用后再继续观察 4周。分别于 0周、4周、8周采血测定血清总胆固醇 (TC)、甘油三酯 (TG)、高密度脂蛋白胆固醇 (HDL C)、载脂蛋白AI(ApoAI)和载脂蛋白B(ApoB)。结果　受试者在服用大杏仁后TC和ApoB明显下降 ,ApoAI 明显升高 ,在Ⅱ型高脂血症患者中TC、LDL C和ApoB均明显下降 ,并且这种作用可持续至少 4周左右。结论　富含单不饱和脂肪酸的美国大杏仁对高脂血症患者的血脂和载脂蛋白水平有良好的调节作用。Objective To observe variations of serum lipid levels in response to a high monounsaturated fatty diet containing almond.Methods A self controlled design was used in the experiment with eighty five hyperlipidemia patients.During the experimental phase,75g almond per day was administrated for 4 weeks.Serum total cholesterol (TC),high density lipoprotein cholesterol (HDL C),triglyceride(TG),apolipoprotein A I and apolipoprotein B (Apo B) were determined at 0,4,8 week.Results After the treatment,TC and Apo B were decreased significantly in total subjects while Apo A I increased.This healthy effect seemed more obvious in Type II hyperlipidemia patients,and low density lipoprotein cholesterol (LDL C) also decreased significantly.Moreover,the lowering effect of lipids last at least 4 weeks.Conclusion Almond had healthy effect on serum lipids and apolipoproteins in hyperlipidemia patients.

关 键 词：富含单不饱和脂肪酸 坚果 高脂血症 血脂 大杏仁 载脂蛋白 

分 类 号：R589.2[医药卫生—内分泌]