全肠外营养在消化道恶性肿瘤术后患者中的应用分析  

Clinical application of total parenteral nutrition in patients with postoperative alimentary tract malignant tumor

作　　者：赵京阳[1] 顾梅[1] 朱长雨[1] 党受涛[1] 

机构地区：[1]首都医科大学附属北京同仁医院肿瘤科,北京100730

出　　处：《首都医科大学学报》2014年第5期657-659,共3页Journal of Capital Medical University

摘　　要：目的评价全肠外营养在消化道恶性肿瘤术后患者中应用的安全性、有效性。方法对27例消化道恶性肿瘤患者术后进行全肠外营养支持,对肠外营养支持前后血清白蛋白、前白蛋白、转铁蛋白的变化进行比较,并观察肠外营养合并症及术后3个月内血癌胚抗原(carcino-embryonic antigen,CEA)、癌抗原199(cancer antigen 199,CA199)的浓度变化。结果全肠外营养后第4、7天,血清白蛋白、前白蛋白水平较前明显升高,血清转铁蛋白在第7天较前明显升高,仅出现1例导管相关性感染,术后3个月内复查血CEA、CA199未见升高。结论对消化道恶性肿瘤术后患者进行全肠外营养是安全、有效的。Objective To evaluate safety and efficacy of total parenteral nutrition（ TPN） in patients with postoperative alimentary malignant tract tumor. Methods Twenty-seven patients with alimentary tract malignant tumor were treated with total parenteral nutrition after operation in oncological department of Beijing Tongren Hospital. Serum levels of albumin,prealbumin and transferrin were compared. Complications of total parenteral nutrition and serum levels of CEA and CA199 in 3 months after operation were observed.Results Serum levels of albumin and prealbumin were higher on the 4thand 7thday. And serum level of transferrin was higher on the 7th day. Only one patient with catheter-related bloodstream infection was observed. Serum levels of CEA and CA199 in 3 months after operation were not elevated. Conclusion Total parenteral nutrition in patients with postoperative alimentary tract tumor is safe and effective.

关 键 词：全肠外营养 消化道恶性肿瘤 肿瘤标志物 内脏蛋白 

分 类 号：R735[医药卫生—肿瘤]