黄粉虫油脂对小鼠体重及学习记忆能力的影响  

Effect of fats from Tenebrio molitor on weight,learning and mnemonic abilities of mice

作　　者：王南溪[1] 杨伟[1] 杨春平[1] 杨桦[1] 史亮[1] 黄敏[1] 龙玲[1] 

机构地区：[1]四川农业大学林学院森林保护省级重点实验室,四川雅安625014

出　　处：《食品工业科技》2015年第1期356-360,共5页Science and Technology of Food Industry

基　　金：四川农业大学"211"工程双支计划项目(00370101)

摘　　要：为了探讨黄粉虫油脂对KM小鼠体重与学习记忆能力的影响,采用电子天平及Morris水迷宫法测试灌胃不同剂量该油脂（0.0095、0.019、0.029m L/（g·d））30d小鼠体重与学习记忆的增效情况。结果显示,灌胃黄粉虫油脂后,小鼠体重增长显著低于对照,且中剂量组增重最少（p〈0.01）;Morris水迷宫实验中,灌胃不同剂量黄粉虫油脂后小鼠的潜伏期比对照缩短10.1%~53.2%,而反应次数多2.7%~64.3%,且中剂量组在潜伏期和反应次数上与对照组有显著的差异（p〈0.05）。表明黄粉虫油脂具有抑制小鼠增重和提高小鼠学习记忆能力的功效,且影响程度与其剂量有关,中剂量（0.019m L/（g·d））为较适剂量。因此,黄粉虫油脂对KM小鼠增重及学习记忆能力的研究,为进一步开发和利用黄粉虫提供了理论依据。To investigate the effect of different doses weight gaining,learning and mnemonic abilities, KM through using electronic balance and Morris water of Tenebrio molitor fats （0.0095,0.019,0.029mL/（ g · d ） ） on mice were intragastric administrated during 30days＇ fats, -maze. Results showed that the weight of mice in group experienced was significantly decreased than those in contrast group, especially with middle dose group adding the least weight （ p 〈 0.01 ）.The period of mice intragastric administrated different doses of Tenebrio monitor iats was found 10.1%-53.2% shorter than that in the contrast group, together with an increased reactive times of 2.7% 64.3% in the Morris water-maze.In addition,those mice with moderate dosage fat performed significant difference （p 〈0.05）,both in the incubation period and the reactive times. It suggested that the fats from Tenebrio molitor could restrain mice＇ s weight growing and enhance their learning and mnemonic abilities which was significantly associated with the dosage intragastric administrated, of which moderate dosage（0.019mL/（ g· d） ）was thought to be the most appropriate. In conclusion, the further development and utilization of Tenebrio molitor could find a theoretical basis from this research.

关 键 词：黄粉虫油脂 MORRIS水迷宫实验 学习记忆能力 KM小鼠 

分 类 号：TS201.4[轻工技术与工程—食品科学]