脑发育不良之病因及早期治疗临床分析  

作　　者：曾繁霞[1] 郭俊清[1] 

机构地区：[1]兰州军区兰州总医院儿科,甘肃兰州730050

出　　处：《河南中医》2014年第B11期161-163,共3页Henan Traditional Chinese Medicine

摘　　要：目的通过对97 例新生儿脑发育不良病例进行分析,总结新生儿脑发育不良的可能原因,探索新生儿脑发育不良的最佳治疗措施.方法：回顾分析2007年1 月至2011 年10 月收住院97 例新生儿脑发育不良的临床资料.依照入组标准选择新生儿脑发育不良病例97 例, 依照诊断标准及临床分型分为轻度28 例,中度46例,重度23 例.对所有患儿资料进行分析,分析97 例新生儿脑发育不良的可能原因,确诊后对患儿进行密切监护,纠正电解质紊乱,恢复脑血流灌注,控制脑水肿,抗惊厥,维持正常脑代谢等治疗,观察患儿治愈情况,为以后的防止工作提供理论依据.结论：围产期脑损伤是新生儿脑发育不良发生的主要原因.做好围产期保健,重视HIE 的防治,对改善预后,减少后遗症,降低新生儿脑发育不良的病死率具有重要的意义.结果：引起新生儿脑发育不良的可能原因依次为窒息69.4%、孕母妊高症31.5%、产程过长23.1%、羊水污染20.4%、胎头负压吸收助产16.7%、宫内胎儿窘迫16.7%、脐带绕颈13%;97 例新生儿脑发育不良病例,治愈67 例,好转20 例,放弃治疗7例,死亡3 例.Objective To analyse the clinical features of 97 cases of Neonatal Brain hypogenesis （neonatal hypoxic-ischemic encephalopathy, HIE） and summarize the correspondingclinical care, the possible causesand prevention and cure measures are presented. Methods： By studying the clinical data of 97 HIE cases from January 2007 to October 2011, whichincluding 28 mild cases, 46 moderate cases, and 23 severe cases acccrding to dignostic criteria and clinical classification, the possible causes are analysed. After confirmeddiagnosis and by closelymonitoring, putting the electrolyte disturbance right, getting brain blood flow back, controlling cerebral edema, anticonvulsion, maintaining thenormal metabolism of brain, etc., to observe the curing process andachieve the theory evidence for prevention of HIE. Results： the possible causes of HIE are 69.4% of asphyxia,31.5% of High Risk Pregnancy, 23.1% of long time parturient, 20.4 of amniotic fluid pollution, 16.7% of Absorption deliver, 16.7% of fetal distress, and 13% of cord around neck.Among the 97 HIE cases, 67 cases were healed, 20 cases werestraightened, 7 cases were abandoned, and 3 cases were died. Conclusion： Perinatal brain injury is the main cause of HIE.It also suggests that proper perinatal health care and improvement of prevention and cure of HIE are of great importance to improve prognosis, decrease sequelae, and reduce mortalityof HIE.

关 键 词：新生儿 脑发育不良 病因 早期治疗 

分 类 号：R748[医药卫生—神经病学与精神病学]