三种骨质疏松自我评价工具应用于广西壮族妇女的筛检效果比较  

Comparison of screening effect between three osteoporosis self-assessment tools for Guangxi Zhuang women

作　　者：王金花[1] 黄秀峰[1] 周庆辉[1] 李海[1] 黄海玲[1] 舒方义[1] 黎飚[1] 陈建海[1] 

机构地区：[1]右江民族医学院人类学研究所,百色533000

出　　处：《解剖学杂志》2014年第6期808-811,共4页Chinese Journal of Anatomy

基　　金：国家自然科学基金（30860117）;广西教育厅科研项目桂教科研[2011]14号（201106LX455）;广西自然科学基金项目桂财教[2013] 19号（2013GXNSFBA019202; 2013GXNSFAA019220）

摘　　要：目的：评价亚洲骨质疏松自我评价工具（OSTA）、我国妇女骨质疏松筛选工具（OSTC）、自建的壮族妇女骨质疏松自我评价工具（OSTZ）与广西壮族围绝经和绝经后妇女骨密度的关系,比较三种工具对骨质疏松症的筛检能力,探讨其临床应用价值.方法：2009年12月～2013年12月采用超声骨密度仪筛选获得580名40岁以上围绝经和绝经壮族妇女的跟骨骨密度数据,利用体质量和年龄分别计算OSTA指数、OSTC指数与自建的OSTZ指数,并进行比较.结果：OSTA指数、OSTC指数、OSTZ指数与跟骨骨密度值均呈正相关（r=0.601;r=0.623;r=0.619）,OSTA与OSTC、OSTZ筛选指数之间呈正相关（r=0.972和r=0.925）,OSTC与OSTZ筛选指数之间呈正相关（r=0.988）.按两级危险程度分类界值进行判定,OSTA、OSTC及OSTZ的灵敏度分别为75.7％、88.0％、98.4％,特异度分别为30.3％、43.9％、67.5％.受试者工作特征曲线下面积为0.727、0.721、0.705,Kappa系数为0.455、0.450、0.322.结论：OSTA与OSTC应用于广西壮族绝经后妇女骨质疏松症的筛查效果均不太理想,临床应用价值受限.OSTZ指数应用于广西壮族围绝经和绝经后妇女骨质疏松症的筛查效果较为理想,有一定的临床应用价值.Objective：To evaluate the relationship between osteoporosis self-assessment tool for Asians （OSTA）,osteoporosis self-assessment tool for Chinese （OSTC）,osteoporosis self-assessment tool for Zhuang （OSTZ） and bone mineral density in Guangxi perimenopausal and postmenopausal women of Zhuang nationality,and to discuss the value of their clinical application through comparison of the screening effect of the three tools in predicting osteoporosis and low bone mass.Methods：During the period of December 2009 to December 2013 with the data of bone mineral density at calcaneus measured by quantitative ultrasound of 580 women aged 40 years and above,OSTA,OSTC and OSTZ risk indexes of each subject were calculated based on their weight and age,and were then compared with each other.Results：The bone mineral density of calcaneus was positively correlated with OSTA,OSTC and OSTZ indexes （r=0.601; r=0.623; r＝ 0.619）,OSTA and OSTC,OSTZ indexes were also correlated positively （r=0.972 and r=0.925）,OSTC and OSTZ indexes were correlated positively （r=0.988,P＜0.001）.According to the two risk levels by these cutoffs,OSTA,OSTC and OSTZ indexes could diagnose osteoporosis with the sensitivity of 75.7％,88.0％,98.4％,the specificity of 30.3％,43.9％,67.5％,the area under recieving operating characteristics curve of 0.727,0.721,0.705,and the Kappa value of 0.455,0.450,0.322,respectively.Conclusion：Both OSTA and OSTC are not ideal tools for screening osteoporosis in Guangxi Zhuang women.OSTZ is a better ideal tool for screening osteoporosis in Guangxi Zhuang perimenopausal and postmenopausal women,and has certain clinical application value.

关 键 词：骨密度 骨质疏松症 骨质疏松自我评价工具 筛检效果 

分 类 号：R737.9[医药卫生—肿瘤]