代谢组学在转基因作物非预期效应评价中的应用  

Applications of Metabolomics in Evaluation of Unintended Effects of Genetically Modified Crops

作　　者：王森[1] 李健爽[1] 杜晓燕[1] 

机构地区：[1]哈尔滨医科大学公共卫生学院,黑龙江哈尔滨150081

出　　处：《食品科学》2014年第9期312-316,共5页Food Science

基　　金：农业部转基因生物新品种培育国家重大科技专项(2011ZX08011-005)

摘　　要：外源基因的非预期效应可能形成新的代谢产物或改变代谢模式,也可能引起转基因作物的营养成分发生改变,甚至可能会产生一些新的有毒物质,是转基因食品安全性评价的重要内容之一。本文主要对近年来代谢组学技术在转基因作物非预期效应评价中的最新应用做了总结,并阐述了对该研究领域的预期,以期促进转基因食品安全性评价体系的发展和完善。Unintended effects from exogenous gene may form new metabolites or change metabolic patterns and nutrients of genetically modified crops, and even generate some new toxic substances. The study on unintended effects is one of the important contents of safety evaluation of genetically modified foods. This review focuses on the latest applications of metabolomics in evaluation of unintended effects of genetically modified crops, and describes research expectations in this field, so as to promote the development and improvement of safety evaluation system for genetically modified foods.

关 键 词：转基因作物 代谢组学 非预期效应 评价 

分 类 号：TS201.6[轻工技术与工程—食品科学]