无抽搐电休克对女性精神分裂症患者心肌酶的影响  

Effects of MECT on myocardial enzyme of female schizo-phrenics

作　　者：寇根生[1] 段德香[1] 程哲[1] 王萍[1] 赵淑芹[1] 邢智广 张红星[1] 

机构地区：[1]新乡医学院第二附属医院,河南新乡453002

出　　处：《临床心身疾病杂志》2014年第4期1-3,共3页Journal of Clinical Psychosomatic Diseases

基　　金：新乡医学院重点学科开放课题（编号ZD200992）

摘　　要：目的：探讨无抽搐电休克治疗对女性精神分裂症患者心肌酶的影响。方法将60例女性精神分裂症患者随机分为两组，每组30例，两组均口服利培酮或奥氮平治疗，研究组在此基础上联合无抽搐电休克治疗。监测两组无抽搐电休克治疗前后心肌酶的变化。结果研究组无抽搐电休克治疗末血清心肌酶各项指标均较治疗前显著升高（ P＜0．05或0．01），且均显著高于对照组（ P＜0．05或0．01）；无抽搐电休克治疗后2周末血清心肌酶各项指标与治疗前比较差异均无显著性（P＞0．05），与对照组比较差异均无显著性（P＞0．05）。结论无抽搐电休克治疗精神分裂症患者可引起心肌酶一过性增高现象。Objective To explore the effects of modified electroconvulsive therapy （MECT） on myocardial enzyme of female schizophrenics .Methods Sixty female schizophrenics were randomly divided into two groups of 30 ones each ,both groups took orally risperidone or olanzapine ,on this basis research group was plus MECT .Pre-and post-MECT myocardial enzyme changes of two groups were monitored .Results All indexes of myocardial enzyme heightened more significantly at the end of MECT compared with pre-MECT in research group （P〈0 .05 or 0 .01） ,those were significant higher than in control group （P〈0 .05 or 0 .01）;pre-and post-treatment （P〉0 .05） and group differences （P〉0 .05） in all indexes of serum myocardial enzyme had no notable statistical significances at the end of the second week after MECT .Conclusion MECT could cause transient increased phenomenon of schizophrenics’ myocardial enzyme .

关 键 词：精神分裂症 心肌酶 无抽搐电休克治疗 联合治疗 抗精神病药物 

分 类 号：R749.3[医药卫生—神经病学与精神病学] R749.054[医药卫生—临床医学]