手动与眼动反应抑制的认知神经机制  

Cognitive and Neural Mechanisms of Response Inhibition in Hand and Eye Movements

作　　者：宣宾[1] 彭苏浩[1] 

机构地区：[1]安徽师范大学心理学系,芜湖241000

出　　处：《生物化学与生物物理进展》2015年第4期329-336,共8页Progress In Biochemistry and Biophysics

基　　金：国家自然基金资助项目(31171076)~~

摘　　要：手动与眼动反应抑制是指抑制与当前环境不相适应的优势手动或眼动反应.与经典的Go/Nogo任务、停止信号任务测量的抑制水平相比,眼动抑制任务可提供更为丰富的指标,并分离出语言及手部运动反应的污染.手动与眼动反应抑制在不同神经精神疾病以及个体发展的不同阶段表现均有不同.额叶-基底神经节网络在手动和眼动抑制中发挥类似的作用,但额下回是手动抑制的关键脑区,额叶眼区和上丘则与眼动抑制关系更密切.目前,主要的争议集中在两者的神经机制、两者涉及的高级认知加工以及在神经心理学和发展心理学中的不同行为表现和发展趋势.Response inhibition of hand and eye-movement is to suppress the inappropriate response in hand and eye. Comparing with the classical paradigms such as Go/Nogo or Stop-signal, response inhibition of eye movement can provide more indices, and can separate from the confusion of verbal or hand movement. Response inhibition of hand and eye-movement differ in some neurological and psychiatric disorders, and the different developmental stages. Fronto-basal ganglia circuit play a similar role in eye and hand inhibition, but IFG is only key for hand response inhibition, and FEF and SC are only key for eye response inhibition. The arguments focused on the neural mechanisms, related higher cognitive activity, and the different performance and tendency in neuropsychology and developmental psychology.

关 键 词：反应抑制 停止信号任务 反向眼跳 额叶-基底神经节模型 

分 类 号：B845[哲学宗教—心理学]