基于不同纳米材料的侧流免疫层析技术在真菌毒素检测中的应用  

Application of Nanoparticle Probe-based Lateral Flow Immunochromatography Technology in Mycotoxins Detection

作　　者：谢艳君[1,2] 杨英[2,3] 孔维军[2] 杨世海[1] 杨美华[2] 

机构地区：[1]吉林农业大学中药材学院,长春130118 [2]中国医学科学院中国协和医科大学药用植物研究所,北京100193 [3]成都中医药大学药学院,成都611137

出　　处：《分析化学》2015年第4期618-628,共11页Chinese Journal of Analytical Chemistry

基　　金：国家自然科学基金(Nos.81274072;81473346);2014中医药行业科研专项(No.201407003)资助~~

摘　　要：真菌毒素毒性强,具有很强的致癌性和致畸性,对人体的危害巨大。近年来,其快速检测技术成为研究的热点,在"批量检测"的趋势下,侧流免疫层析技术以具有操作简便,经济合理,灵敏快速等优点,广泛应用于食品、饲料、农产品中真菌毒素的检测。本文对侧流免疫层析检测技术的研究概况及不同纳米材料的侧流免疫层析技术在真菌毒素检测中的应用和发展前景进行综述,以期为侧流免疫层析技术在真菌毒素检测的未来发展及应用提供参考。Mycotoxins,the secondary metabolites of fungi,are generally recognized as potent carcinogens and teratogens with great harm to human health. Under the trend of ‘batch testing ＇, lateral flow immunochromatography（ LFIC） technique has been widely used for the detection of mycotoxins in foods,feeds,and agricultural products because of its simplicity,low cost and rapidness. In this paper,the current research progress of LFIC is reviewed. The recent application advances of LFIC with various nanomaterial labeled in the detection of mycotoxins are overviewed and prospected. This review will provide useful references for the future development and application of LFIC for mycotoxin detection.

关 键 词：纳米材料 侧流免疫层析 真菌毒素 综述 

分 类 号：TS207.4[轻工技术与工程—食品科学]