沙丁胺醇在动物体内代谢残留规律及监管技术研究进展  

Research Advancement of Residue,Depletion and Monitoring Technology of Salbutamol in Animal Body

作　　者：张凯[1,2] 张军民[1,2] 赵青余[1,2] 汤超华 梁晓维[1,2,3] 

机构地区：[1]中国农业科学院北京畜牧兽医研究所/农业部华北动物遗传资源与营养科学观测实验站,北京100193 [2]中国农业科学院世界农用林业中心农用林业与可持续畜牧业联合实验室,北京100193 [3]甘肃农业大学动物科学技术学院,兰州730070

出　　处：《中国食物与营养》2015年第5期9-13,共5页Food and Nutrition in China

基　　金：公益性行业(农业)科研专项经费资助(项目编号:201203088-03)

摘　　要：沙丁胺醇是一种选择性β-兴奋剂,可减少动物脂肪沉积、提高胴体瘦肉率,同时,沙丁胺醇易在动物肌肉和内脏器官中蓄积残留而引起食物中毒。从1997年起我国就明令禁止沙丁胺醇用作饲料添加剂,然而近十几年来"瘦肉精"中毒事件仍屡禁不止,严重影响了我国食品安全。因此,本文综述了沙丁胺醇代谢动力学、在动物组织器官中的残留消除规律及监管技术的研究进展,为更好地监管沙丁胺醇在畜禽养殖环节违法添加提供科学依据。Salbutamol （SAL） is a selective beta-agonist and can cause dramatic increase in the partition of carcass lean and reduction in body fat, however, it is easy to accumulate in muscle and organs of animal body. Since 1997, salbutamol was banned for using as feed additive, yet the clenbuterol poisoning incidents were repeated failure to prohibit, it was seriously threatening the domestic food safe- ty. According to the pharmacokinetics of salbutamol, its residues and depletion in organs of animal body and monitor technologies were ve- viewed to provide scientific basis for the better salbutamol abuse monitoring in livestock and oouhrv oroduction.

关 键 词：沙丁胺醇 代谢动力学 残留消除规律 监管技术 

分 类 号：TS201.6[轻工技术与工程—食品科学]