围头湾5种海藻提取物AChE抑制活性与DPPH·清除能力的比较  

Acetyl Choline Enzyme Inhibitory Activity and DPPH· Radical Scavenging Capacity of the Extracts from Five Seaweeds in Fujian Weitou Bay

作　　者：黄晓冬[1] 李裕红[1] 黄晓昆[1] 戴聪杰[1] 

机构地区：[1]泉州师范学院近海资源生物技术福建省高校重点实验室,福建泉州362000

出　　处：《泉州师范学院学报》2015年第2期27-32,共6页Journal of Quanzhou Normal University

基　　金：福建省自然科学基金海洋经济发展专项重点项目(2014N0017);泉州市科技计划项目资助(2014Z129)

摘　　要：对福建省围头海域5种海藻提取物及萃取部位的乙酰胆碱酶抑制活性与DPPH·清除能力进行比较研究,并分别测定其总酚与总黄酮含量.结果表明:裙带菜与羊栖菜提取物具有较高含量的总酚与总黄酮;裙带菜的乙酸乙酯部位、二氯甲烷部位和羊栖菜石油醚部位、二氯甲烷部位在10mg/mL质量浓度时表现出较强的乙酰胆碱酶抑制活性,并且裙带菜乙酸乙酯部位、二氯甲烷部位以及羊栖菜二氯甲烷部位的DPPH·清除能力均明显高于其他提取物或萃取部位.The acetyl choline enzyme inhibitory activity and DPPH · radical scavenging capacity of the extracts and its solvent fraction from five kinds of seaweed in Fujian Weitou bay were studied.Results showed that the exracts from Undaria pinnatifida and Sargassurn fusiforme had higher concentra tion of polyphenols and flavonoids. Ethyl acetate fraction and methylene chloride fraction from Un- daria pinnatifida,petroleum ether fraction and dichloromethane fraction from Sargassum fusiforme had strong acetyleholine enzyme inhibitory activity at 10 mg/mL.At the concentration of 1 mg/mL, the DPPH · scavenging abilities of ethyl acetate fraction and methylene chloride fraction from Un daria pinnatifida ,dichloromethane fraction from Sargassurn fusiforme were higher than other ex- tracts or fractions.

关 键 词：海藻 提取物 乙酰胆碱酯酶抑制活性 DPPH·自由基 

分 类 号：R931.71[医药卫生—生药学]