赖氨酸锗与老年性智力障碍  

Lysine germanium and senile intelligence disturbance

作　　者：严忠浩 陈明[2] 王信成[3] 俞霭瑶[2] 孙琛[2] 邱浦东 

机构地区：[1]上海市老年人康复中心 [2]上海第二医科大学 [3]上海职工医学院

出　　处：《中国康复医学杂志》1991年第2期54-57,共4页Chinese Journal of Rehabilitation Medicine

摘　　要：老年人中有不同程度智力障碍者约占65岁以上老人的10％,国内外目前尚缺乏有效的防治方法。应用微量元素化合物赖氨酸锗对提高老年智力进行动物实验研究和临床观察,结果表明赖氨酸锗可提高老年小鼠空间分辨的学习记忆能力。30例老年性智力障碍患者,服用赖氨酸锗3个月后,提高智力有效率达60％,显效率达20％。By using Three-Arm Equilength Y-Mase test, the learning and memory ability of spatial discrimination was studied on aged mice after lysine germanium (Ge-401) administration. The result showed that Ge-401 could improve the learning and memory ability and give dose-dependent relationship. 30 patients suffered from senile intelligence disturbance were tested by using Memory Scale for senile dementia examination. 3 months after Ge-401 ad- ministration (25mg/t.i.d×90 days) the patients' intelligence as markedly improved. The effective rate 60％ and significantly effective rate 20％ were observed.

关 键 词：智力障碍 赖氨酸锗 老年人 

分 类 号：R749.160.1[医药卫生—神经病学与精神病学]