饱和脂肪酸对昆明小鼠口腔溃疡愈合影响的研究  

Research on the effects of saturated fatty acids on the recovery of Aphthous Ulcer in Kunming mice

作　　者：洪海鑫[1] 张雨濛[2] 陶思颖[1] 周欣奕[1] 周瑜[1] 

机构地区：[1]四川大学华西口腔医学院.口腔疾病研究国家重点实验室,四川成都610000 [2]四川大学基础医学与法医学院,四川成都610000

出　　处：《临床口腔医学杂志》2015年第6期335-337,共3页Journal of Clinical Stomatology

基　　金：国家自然科学基金(81470747;81102060);四川大学"大学生创新创业训练计划"(20140786)

摘　　要：目的：研究饱和脂肪酸对昆明小鼠口腔溃疡愈合的影响。方法：3组3～5周龄昆明小鼠，用40％冰醋酸制造口腔溃疡，3组鼠分别喂养含有不同浓度饱和脂肪酸的饲料，观察其对口腔溃疡愈合的影响。结果：实验组动物口腔溃疡愈合时间明显长于对照组，高脂组口腔溃疡愈合时间较对照组延长12 d。结论：饱和脂肪酸对昆明小鼠口腔溃疡有着明显的延缓愈合的作用。Objective：To study the effects of saturated fatty acids on the animal model of Aphthous Ulcer. Method：Aphthous Ulcer was induced in 3 groups of Kunming mice aged 3~5 weeks.The 3 groups of mice were respectively fed with 3 kinds of feedstuff which contained different concentrations of saturated fatty acids,and the healing of the 3 groups of mice was observed. Result：The average cure period in the experimental groups was significantly longer than that of control group,the average cure period in the group fed with high concentration of saturated fatty acids was 12 days longer than that of control group. Conclusion：Saturated fatty acids had significant effects on extending the cure period of Aphthous Ulcer in Kunming mice.

关 键 词：口腔溃疡 动物模型 昆明小鼠 饱和脂肪酸 

分 类 号：R781.5[医药卫生—口腔医学]