吹扫捕集-气质联用法对婴幼儿橡胶奶嘴中挥发性潜在迁移物的高通量筛查  

High Throughput Screening of Volatile Potential Migrations in Infant Nipples by Purge&Trap and Gas Chromatography-Mass

作　　者：封棣[1] 杨慧敏[1] 栗真真 王凤寰[1] 

机构地区：[1]北京工商大学食品学院食品添加剂与配料北京市高等学校工程中心北京市食品风味化学重点实验室食品质量与安全北京实验室,北京100048

出　　处：《中国食品学报》2015年第4期164-174,共11页Journal of Chinese Institute Of Food Science and Technology

基　　金：国家自然科学基金项目(31301465);科研基地建设-科技创新平台-国家自然科学基金配套(市级)(19005418040);北京市优秀人才培养资助项目(2012D005003000001)

摘　　要：利用吹扫捕集-气相色谱/质谱技术,建立了27种婴幼儿奶嘴中挥发性潜在迁移物的高通量筛选检测平台及数据库,系统优化了吹扫捕集参数和气质联用分析条件。利用质谱NIST 11谱库对色谱峰进行检索定性,并对结果进行归类及数据分析。列出检出物质的相关法规、限制及可能来源,提出重点关注物质。从27种样品中共检测出98种涉及11类的化学物质,其中重点关注的物质有裂解产物、助剂及单体。该法简便、快捷、灵敏、环境友好,适用于食品接触橡胶制品中挥发性潜在迁移物的筛查。通过对98种潜在迁移物的数据库的分析,婴幼儿奶嘴中潜在迁移物成分复杂,欧盟法规中未列出、未评估及有检出限量的物质被检出,给婴幼儿健康带来重大安全隐患。物质的确证定量,在食品中的迁移行为及其风险评估将是今后的研究焦点。Establish a high-throughput screening test platform and the database of the volatile potential migrants in27 kinds of infant rubber nipples by Purge Trap and gas chromatography-mass technique. The analysis conditions of Purge Trap and GC-MS were optimized and the chromatographic peaks were qualitatived by NIST 11 spectrum library of mass spectrometry. The potential migrants were classified and the relevant regulations, restrictions and possible origins were listed in the database. 98 chemical substances involved 11 categories were detected from 27 samples, which some split products, additives and monomers were emphasized as high focus substances. The method is simple, rapid, sensitive, eco-friendly and suitable for the high-throughput screening test of the volatile potential migrants of food contact rubber products. The ingredients of potential migrants in the database are complicated. Some substances not listed, not evaluated or with limited requirements were found, which is harmful to the infants, health. The confirmation and quantification, the migration behavior in foods and risk assessment for the emphasized substances will be the research focus in the future.

关 键 词：婴幼儿奶嘴 挥发性 潜在迁移物 吹扫捕集 气相色谱/质谱技术 

分 类 号：O657.63[理学—分析化学] TQ336.7[理学—化学]