Improving recognition of hepatic perivascular epithelioid cell tumor:Case report and literature review  

作　　者：Toshiya Maebayashi Katsumi Abe Takuya Aizawa Masakuni Sakaguchi Naoya Ishibashi Osamu Abe Tadatoshi Takayama Hisashi Nakayama Shunichi Matsuoka Kazushige Nirei Hitomi Nakamura Masahiro Ogawa Masahiko Sugitani 

机构地区：[1]Department of Radiology,Nihon University School of Medicine,Itabashi-ku,Tokyo 173-8610,Japan [2]Department of Digestive Surgery,Nihon University School of Medicine,Itabashi-ku,Tokyo 173-8610,Japan [3]Department of Gastroenterology and Hepatology,Nihon University School of Medicine,Itabashi-ku,Tokyo 173-8610,Japan [4]Department of Pathology,Nihon University School of Medicine,Itabashi-ku,Tokyo 173-8610,Japan

出　　处：《World Journal of Gastroenterology》2015年第17期5432-5441,共10页世界胃肠病学杂志（英文版）

摘　　要：A 58-year-old man presented with the chief complaint of abdominal bloating and was incidentally found to have a liver tumor.As diagnostic imaging studies could not rule out malignancy,the patient underwent partial resection of segment 3 of the liver.The lesion pathologically showed eosinophilic proliferation,in addition to immunohistochemical positivity for human melanoma black 45 and Melan-A,thereby leading to the diagnosis of a hepatic perivascular epithelioid cell tumor(PEComa).A PEComa arising from the liver is relatively rare.Moreover,the name ‘PEComa' has not yet been widely recognized,and the same disease entity has been called epithelioid angiomyolipoma(EAML),further diminishing the recognition of PEComa.In addition,PEComa imaging findings mimic those of malignant liver tumors,and clinically,this tumor tends to enlarge.Therefore,a PEComa is difficult to diagnose.We conducted a systematic review of PEComa and EAML cases and discuss the results,including findings useful for differentiating perivascular epithelioid cell tumors from malignant liver tumors.A 58-year-old man presented with the chief complaint of abdominal bloating and was incidentally found to have a liver tumor.As diagnostic imaging studies could not rule out malignancy,the patient underwent partial resection of segment 3 of the liver.The lesion pathologically showed eosinophilic proliferation,in addition to immunohistochemical positivity for human melanoma black 45 and Melan-A,thereby leading to the diagnosis of a hepatic perivascular epithelioid cell tumor(PEComa).A PEComa arising from the liver is relatively rare.Moreover,the name ‘PEComa' has not yet been widely recognized,and the same disease entity has been called epithelioid angiomyolipoma(EAML),further diminishing the recognition of PEComa.In addition,PEComa imaging findings mimic those of malignant liver tumors,and clinically,this tumor tends to enlarge.Therefore,a PEComa is difficult to diagnose.We conducted a systematic review of PEComa and EAML cases and discuss the results,including findings useful for differentiating perivascular epithelioid cell tumors from malignant liver tumors.

关 键 词：ANGIOMYOLIPOMA Tuberous SCLEROSIS MELAN-A PERIVASCULAR EPITHELIOID cell tumor Humanmelanoma black 45 Imaging 

分 类 号：R735.7[医药卫生—肿瘤]