刺参内脏蛋白酶解液抗氧化活性研究  

Studies on Antioxidant Activities of Protein Hydrolysates from Sea Cucumber Viscera

作　　者：陶海英[1] 闫鸣艳[2] 尹利端 

机构地区：[1]山东省农业科学院畜牧兽医研究所,山东济南250100 [2]中国科学院烟台海岸带研究所,山东烟台264003 [3]烟台新时代健康产业有限公司,山东烟台264006

出　　处：《食品研究与开发》2015年第11期58-61,共4页Food Research and Development

基　　金：烟台市科技发展计划"刺参内脏抗氧化肽制备工艺及活性研究"(2011070);山东省海洋经济创新发展区域示范项目"海洋活性蛋白及其功能制品的开发与产业化"

摘　　要：采用小鼠D-半乳糖致衰老模型,通过测定小鼠肝脏和心脏中的超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)活性和丙二醛(MDA)含量,进一步研究了刺参内脏蛋白酶解物酶解物的抗氧化活性。表明灌胃200 mg/kg·d酶解物可明显提高小鼠肝脏和心脏中SOD和GSH-Px活力,并显著降低MDA含量。说明刺参内脏蛋白酶解物在一定程度上能够提高D-半乳糖模型衰老小鼠的抗氧化能力。D-galactose subacute aging model of mice was built up for further on studying the antioxidant activities of protein hydrolysates from sea cucumber viscerahydrolysates , the capacity of SOD and GSH-Px and MDA content of mice in liver and heart were detected. Results showed that： the levels of SOD and GSH-Px activity were obviously increased in liver and heart of mice after fed hydrolysates 200 mg/kg·d every day, and MDA content was obviously decreased, suggesting that there was a remarkable antioxidant effect of protein hydrolysates from sea cucumber viscera on D-galactose subacute aging model mice.

关 键 词：刺参 内脏 酶解液 抗氧化活性 

分 类 号：R285.5[医药卫生—中药学]