人参中二氧化硫残留分析与健康风险评估  

Analysis and Health Risk Assessment of Sulfur Dioxide Residue in Ginseng Roots

作　　者：王艳红[1] 安宇[2] 张敏[1] 吴晓民[3] 任谓明[1] 许煊炜[1] 朱艳萍[1] 赵丹[1] 李月茹[1] 

机构地区：[1]吉林农业大学农业部参茸产品质量监督检验测试中心,吉林长春130118 [2]吉林农业大学生命科学学院,吉林长春130118 [3]吉林农业大学附属医院,吉林长春130118

出　　处：《食品科学》2015年第24期214-219,共6页Food Science

基　　金：国家级大学生创新创业训练计划项目(201310193047)

摘　　要：分析不同类型人参中二氧化硫残留状况,并结合分析结果对人参途径摄入的二氧化硫进行健康风险评估。在东北地区不同的人参市场共采集4种类型80个人参样品,利用荧光衍生法测定人参中二氧化硫的残留量;采用点评估和基于蒙特卡洛(Monte Carlo)模拟法的概率评估评价人参中二氧化硫的暴露风险水平。结果表明:4种类型人参中二氧化硫的残留量按我国人参国家标准的限量值50 mg/kg规定,部分样品超出限量值。但不同种类人参二氧化硫含量不同,二氧化硫平均含量顺序为生晒参(89.16 mg/kg)>保鲜参(62.70 mg/kg)>红参(45.01 mg/kg)>人参蜜片(40.94 mg/kg),且生晒参与红参或人参蜜片差异显著。点评估(按平均值估计)结果显示,被调查的居民通过人参途径摄入二氧化硫的日均暴露量分别为1.08×10-2(保鲜参)、8.35×10-3(生晒参)、4.46×10-3 mg/(kg·d)(红参)及2.83×10-3 mg/(kg·d)(人参蜜片),风险系数值均小于1;概率评估结果显示,用来衡量高暴露人群的最高暴露量位点99.5%分位处,保鲜参、生晒参、红参和人参蜜片二氧化硫暴露量分别为0.039 3、0.158 2、0.026 1 mg/(kg·d)和0.019 4 mg/(kg·d),风险系数虽远高于均值,但都远远小于1,表明风险系数虽然增大了,但仍处于安全水平内。可见,现今不同类型人参中二氧化硫的含量对普通人群甚至高危人群均无明显健康风险。This study aimed to analyze the status of sulfur dioxide residue in different types of ginseng roots and to assess the health risk of sulfur dioxide residue based on the obtained data. A total of 80 samples of four types of ginseng roots were obtained from different ginseng markets in northeast China and prepared for analysis by fluorometry after derivatization. Exposure assessments of sulfur dioxide residue in ginseng roots were carried out by point assessment and probabilistic assessment based on Monte Carlo simulation method. The results showed that sulfur dioxide contents of some samples exceeded the maximum residue level stipulated the Chinese national standard for sulfur dioxide （50 mg/kg）. The average concentrations of sulfur dioxide in four types of ginseng roots were 62.70 mg/kg for preserved fresh ginseng, 89.16 mg/kg for dried raw ginseng, 45.01 mg/kg for red ginseng and 40.94 mg/kg for honeyed ginseng slice, respectively, indicating a significant difference between dried raw ginseng and red ginseng or honeyed ginseng slice. The point estimation based on the mean intake and residue showed that the daily exposure to sulfur dioxide due to ginseng consumption of the investigated inhabitants were 1.08 × 10- 2 mg/（kg-d） for preserved fresh ginseng, 8.35 × 10 -3 mg/（kg＇d） for dried raw ginseng, 4.46 ~ 10 3 mg/（kg.d） for red ginseng and 2.83 ~ 10 3 mg/（kg.d） for honeyed ginseng slice, respectively. Their hazard quotients were all less than one. The results of probabilistic assessment showed that when the highest exposure site （99.5%） was used to measure the high exposure population, the daily exposure of sulfur dioxide in preserved fresh ginseng, dried raw ginseng, red ginseng and honeyed ginseng slice were 0.039 3, 0.158 2, 0.026 1 and 0.019 4 mg/（kg.d）, respectively. The hazard quotients were far higher than the average but far lower than one. These results indicated that they were still at a safe level though their health risks were increased. Thus the levels of sulfur dioxi

关 键 词：人参 二氧化硫 蒙特卡洛 健康风险评估 

分 类 号：R155[医药卫生—营养与食品卫生学]