类球红细菌分批发酵生产辅酶Q_(10)的动力学模型  

Batch Fermentation Kinetic Model of CoQ_(10) Producing by Rhodobacter sphaeroides

作　　者：柯崇榕[1] 钟璐芳 叶剑雄[2] 杨威[1] 邵庆伟[1] 黄建忠[1] 

机构地区：[1]福建师范大学工业微生物教育部工程研究中心生命科学学院,福建福州350108 [2]福建师范大学数学与计算机科学学院,福建福州350108

出　　处：《生物数学学报》2016年第1期65-70,共6页Journal of Biomathematics

基　　金：福建省教育厅项目(JB12037);福建省自然科学基金项目(No.2014J01037)

摘　　要：研究了Rhodobacter sphaeroidesEIM-8发酵生产CoQ_(10)的代谢特性.根据Monod、Logistic和Luedeking-Piret方程建立菌体细胞生长、CoQ_(10)积累和葡萄糖消耗的动力学模型,并采用进化规划求得模型参数.模型模拟计算结果与试验值拟合良好,平均相对误差均在7%以内,较好地反映了类球红细菌分批发酵过程的动力学特征.The batch fermentation kinetics of Rhodobacter sphaeroides EIM-8 for CoQ10 production was investigated. A kinetic model for cell growth, CoQ10 formation and sugar consumption was proposed according to the Monod, Logistic and Luedeking-Piret equations. Kinetic parameters were evaluated by evolution programming and the model appears to provide a reasonable description for the fermentation process, in which the deviations between model calculating results and experimental data are within 7%.

关 键 词：类球红细菌 辅酶Q10 发酵 动力学模型 

分 类 号：Q939.97[生物学—微生物学]