跨病种研究对精神疾病诊断标准的影响（英文）  

Influence of cross-disorder analyses on the diagnostic criteria of mental illnesses

作　　者：王媺媞 崔东红 

机构地区：[1]Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine

出　　处：《上海精神医学》2016年第1期45-47,共3页Shanghai Archives of Psychiatry

基　　金：supported by the National Natural Science Foundation of China(81271481 and 81171266);the Shanghai Jiao Tong University Science and Social Science Intersection Program(14JCR205);the Shanghai key laboratory of psychotic disorders(13dz2260500)

摘　　要：概述:许多跨病种研究逐渐发现在不同的常见精神疾病之间——包括精神分裂症、双相情感障碍、和抑郁症,存在共同的遗传变异,而目前诊断系统中已经将这些疾病分为独立的精神障碍。这些跨病种研究对基于临床症状的精神障碍诊断传统系统是一种挑战,但是这否能够成为精神疾病分类的一种改进方法从而改善这些承受痛苦的患者的预后仍有待观察。Cross-disorder studies are identifying shared genetic variations among common mental illnesses – including schizophrenia, bipolar disorder, and major depression – which are classified as independent disorders in the current diagnostic system. These cross-disorder studies are challenging the traditional system of diagnosing mental disorders based on clinical symptoms, but it remains to be seen whether or not they will lead to an improved method of classifying psychiatric disorders that can, in turn, lead to better outcomes for individuals suffering from these conditions.

关 键 词：跨障碍分析 精神疾病 遗传学 诊断 

分 类 号：R749[医药卫生—神经病学与精神病学]