Copper（I）-Catalyzed 3-Position Methylation of Coumarins by Using Di-tert-butyl Peroxide as the Methylation Reagents  

作　　者：Huan Zhuang Runsheng Zeng Jianping Zou 

机构地区：[1]Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou, Jiangsu 215123, China

出　　处：《Chinese Journal of Chemistry》2016年第4期368-372,共5页中国化学（英文版）

摘　　要：The copper-catalyzed methylation of coumarin by using di-tert-butyl peroxide （DTBP） has been described. The reaction provides direct access to a wide range of 3-methylcoumarins in moderate to good yields. In this procedure, it is noteworthy that DTBP was employed not only as the oxidant, but also as the methyl source.The copper-catalyzed methylation of coumarin by using di-tert-butyl peroxide （DTBP） has been described. The reaction provides direct access to a wide range of 3-methylcoumarins in moderate to good yields. In this procedure, it is noteworthy that DTBP was employed not only as the oxidant, but also as the methyl source.

关 键 词：CuCl di-tert-butyl peroxide METHYLATION COUMARIN 

分 类 号：TQ325.14[化学工程—合成树脂塑料工业] TQ655