中老年女性血清铁蛋白(SF)水平与年龄和体质指数(BMI)之间的关系的流行病学研究（英文）  

An Epidemiological Study of the Relationship of Serum Ferritin Level between Age and Body Mass Index among Mid-old Women

作　　者：贾茹[1] 王燕[2] 马爱国[1] 郭郡[2] 孙晓岚[2] 张冠军 张华琦[1] 

机构地区：[1]青岛大学医学院营养研究所,山东青岛266021 [2]青岛大学附属医院,山东青岛266021 [3]东明县人民医院,山东菏泽274500

出　　处：《现代生物医学进展》2016年第16期3100-3104,共5页Progress in Modern Biomedicine

基　　金：Natural Science Foundation of China(81373000)~~

摘　　要：目的:评估中老年女性血清铁蛋白(SF)水平与年龄和体质指数(BMI)之间的关系。方法:选自中国4046名健康女性进行横断面研究,受试者年龄均在45-70岁并签署了知情同意书。所有受试者血清铁蛋白水平采用放射免疫分析法测定。采用Spearman秩相关检验分析血清铁蛋白与各指标之间的相关性。不同组别SF差异的显著性用Kruskal-Wallis秩和检验来比较。结果:Spearman相关性分析显示血清铁蛋白与年龄(r=0.425;p<0.05)和BMI(r=0.238;p<0.05)均呈正相关。Kruskal-Wallis秩和检验显示不同年龄组和不同BMI组的血清铁蛋白水平均有显著性差异(p<0.05)。65-70岁人群的血清铁蛋白平均水平比45-50岁人群高出近两倍。并且肥胖人群中血清铁蛋白水平要远远高于偏瘦人群。结论:中老年女性铁储存的增加与年龄的增长和体质指数的增加呈现正相关关系。Objective： To evaluate the relationship of serum ferritin （SF） level between age and body mass index （BMI） among mid-old women. Methods： This cross-sectional study was done among 4046 healthy women in China who were in age of 45-70 and announced their readiness to participate in the study. SF concentration was measured with an automated radioimmunoassay analyzer in all the subjects. Spearman＇s correlation test was used to determine the relationship between SF and other indicators. Differences of SF between different groups were compared by Kruskal-Wallis＇s rank sum test. Results： Spearman correlation analysis showed a positive correlation between SF with age （r = 0.425; P 〈 0.05）, BMI （r = 0.238; P 〈 0.05）. Kruskal-Wallis rank sum test showed significant difference between different age groups and different BMI groups （P 〈 0.05）. The median SF concentration in 65-70 year old was nearly two times higher than that of 45-50 year old. And in obese people were far higher than that of lean people. Conclusion： These findings suggest that the increase of iron storage may have a significant positive correlation with aging and BMI values in mid-old women.

关 键 词：血清铁蛋白 年龄 体质指数 女性 

分 类 号：R151.3[医药卫生—营养与食品卫生学]