基于CT脑动脉瘤三维重建及血流场特征分析  

CT-based 3D reconstruction of cerebral aneurysm and the hemodynamic characteristics of its blood flow field

作　　者：刘小月[1] 木合塔尔.克力木 巨刚[1] 

机构地区：[1]新疆大学机械工程学院,乌鲁木齐830047

出　　处：《介入放射学杂志》2016年第7期635-639,共5页Journal of Interventional Radiology

基　　金：新疆维吾尔自治区自然科学基金(2013211A020)

摘　　要：目的评估脑动脉瘤植入支架前后的血流场血流动力学特征,为患者提供可行治疗方案。方法根据CT影像数据和逆向工程等软件建立脑动脉瘤三维实体模型,设计个体化血管内支架模型并植入脑动脉瘤,进行双向流固耦合分析。结果获取支架植入前后脑动脉瘤模型血流速度矢量、流线,动脉瘤壁面剪切力、压力和变形分布图。结论相同工况下,支架植入后脑动脉瘤内主要血流动力学参数均较植入前明显降低,尤其是壁面剪切力对脑动脉瘤壁的影响,可用于分析脑动脉瘤破裂机制,为临床治疗方案选择提供依据。Objective To evaluate the hemodynamic characteristics of blood flow field in cerebral aneurysms before and after stent implantation in order to provide feasible treatment options for the patients with cerebral aneurysm. Methods Based on CT imaging data and by using reverse engineering and other software, three dimensional solid model of cerebral aneurysm was established. Individualized intravascular stent model was designed and implanted in the intracranial aneurysm. Two way fluid-solid coupling analysis was conducted. Results The distributions of flow velocity vector, streamline, wall shear stress, wall pressure and wall deformation of the cerebral aneurysm model were determined before and after stent implantation. Condusion Under the same condition, after stent implantation the main hemodynamic parameters in cerebral aneurysm are significantly decreased if compared with those measured before implantation ; and the effect of wall shear stress on the wall of cerebral aneurysm is of particular value, which can be used to analyze the mechanism of cerebral aneurysm rupture and can also provide the basis for the selection of clinical treatment options.

关 键 词：脑动脉瘤 CT影像 血管内支架 血流动力学 流固耦合 

分 类 号：R743[医药卫生—神经病学与精神病学] R816.1[医药卫生—临床医学]